2GTD

Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004594	molecular_function	pantothenate kinase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0015937	biological_process	coenzyme A biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0043169	molecular_function	cation binding
A	0046872	molecular_function	metal ion binding
B	0004594	molecular_function	pantothenate kinase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0015937	biological_process	coenzyme A biosynthetic process
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0043169	molecular_function	cation binding
B	0046872	molecular_function	metal ion binding
C	0004594	molecular_function	pantothenate kinase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0015937	biological_process	coenzyme A biosynthetic process
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0043169	molecular_function	cation binding
C	0046872	molecular_function	metal ion binding
D	0004594	molecular_function	pantothenate kinase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0015937	biological_process	coenzyme A biosynthetic process
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0043169	molecular_function	cation binding
D	0046872	molecular_function	metal ion binding
E	0004594	molecular_function	pantothenate kinase activity
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0015937	biological_process	coenzyme A biosynthetic process
E	0016301	molecular_function	kinase activity
E	0016310	biological_process	phosphorylation
E	0043169	molecular_function	cation binding
E	0046872	molecular_function	metal ion binding
F	0004594	molecular_function	pantothenate kinase activity
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0015937	biological_process	coenzyme A biosynthetic process
F	0016301	molecular_function	kinase activity
F	0016310	biological_process	phosphorylation
F	0043169	molecular_function	cation binding
F	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Proton acceptor => ECO:0000255

Chain	Residue	Details
A	ASP108
B	ASP108
C	ASP108
D	ASP108
E	ASP108
F	ASP108

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site_id	SWS_FT_FI2
Number of Residues	18
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP9
D	ASP9
D	GLY106
D	THR182
E	ASP9
E	GLY106
E	THR182
F	ASP9
F	GLY106
F	THR182
A	GLY106
A	THR182
B	ASP9
B	GLY106
B	THR182
C	ASP9
C	GLY106
C	THR182

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	ASP128
E	THR131
F	ASP128
F	THR131
A	THR131
B	ASP128
B	THR131
C	ASP128
C	THR131
D	ASP128
D	THR131
E	ASP128

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