2GSX
Complement Receptor Type 2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001618 | molecular_function | virus receptor activity |
| A | 0001848 | molecular_function | complement binding |
| A | 0002376 | biological_process | immune system process |
| A | 0002430 | biological_process | complement receptor mediated signaling pathway |
| A | 0002456 | biological_process | T cell mediated immunity |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004875 | molecular_function | complement receptor activity |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006955 | biological_process | immune response |
| A | 0006957 | biological_process | complement activation, alternative pathway |
| A | 0006958 | biological_process | complement activation, classical pathway |
| A | 0016020 | cellular_component | membrane |
| A | 0030183 | biological_process | B cell differentiation |
| A | 0034987 | molecular_function | immunoglobulin receptor binding |
| A | 0042100 | biological_process | B cell proliferation |
| A | 0042113 | biological_process | B cell activation |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043235 | cellular_component | receptor complex |
| A | 0045087 | biological_process | innate immune response |
| A | 0045959 | biological_process | negative regulation of complement activation, classical pathway |
| A | 0046718 | biological_process | symbiont entry into host cell |
| A | 0060337 | biological_process | type I interferon-mediated signaling pathway |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 950 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 63 |
| Details | Domain: {"description":"Sushi 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 59 |
| Details | Domain: {"description":"Sushi 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 60 |
| Details | Domain: {"description":"Sushi 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 60 |
| Details | Domain: {"description":"Sushi 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 70 |
| Details | Domain: {"description":"Sushi 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 59 |
| Details | Domain: {"description":"Sushi 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 59 |
| Details | Domain: {"description":"Sushi 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 55 |
| Details | Domain: {"description":"Sushi 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 70 |
| Details | Domain: {"description":"Sushi 9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 59 |
| Details | Domain: {"description":"Sushi 10","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 56 |
| Details | Domain: {"description":"Sushi 11","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 64 |
| Details | Domain: {"description":"Sushi 12","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 59 |
| Details | Domain: {"description":"Sushi 13","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 60 |
| Details | Domain: {"description":"Sushi 14","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 60 |
| Details | Domain: {"description":"Sushi 15","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12122212","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LY2","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 8 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
