2GQR
SAICAR Synthetase Complexed with ADP-Mg2+
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009236 | biological_process | cobalamin biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016874 | molecular_function | ligase activity |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0009236 | biological_process | cobalamin biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016874 | molecular_function | ligase activity |
| B | 0097216 | molecular_function | guanosine tetraphosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 239 |
| Chain | Residue |
| A | ADP238 |
| A | HOH240 |
| A | HOH241 |
| A | HOH242 |
| A | HOH243 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 239 |
| Chain | Residue |
| B | HOH243 |
| B | ADP238 |
| B | HOH240 |
| B | HOH241 |
| B | HOH242 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP A 238 |
| Chain | Residue |
| A | TYR8 |
| A | GLY10 |
| A | LYS11 |
| A | ALA12 |
| A | LYS13 |
| A | VAL15 |
| A | LEU24 |
| A | GLN69 |
| A | LYS82 |
| A | LEU84 |
| A | MSE86 |
| A | LYS123 |
| A | GLU179 |
| A | ASP191 |
| A | MG239 |
| A | HOH240 |
| A | HOH242 |
| A | HOH243 |
| A | HOH256 |
| A | HOH266 |
| A | HOH291 |
| A | HOH343 |
| A | HOH354 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ADP B 238 |
| Chain | Residue |
| B | TYR8 |
| B | GLY10 |
| B | LYS11 |
| B | ALA12 |
| B | LYS13 |
| B | VAL15 |
| B | LEU24 |
| B | GLN69 |
| B | VAL81 |
| B | LYS82 |
| B | LEU84 |
| B | MSE86 |
| B | LYS123 |
| B | GLU179 |
| B | ASP191 |
| B | MG239 |
| B | HOH240 |
| B | HOH242 |
| B | HOH243 |
| B | HOH251 |
| B | HOH311 |
| B | HOH324 |
| B | HOH336 |
Functional Information from PROSITE/UniProt
