Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2GLJ

crystal structure of aminopeptidase I from Clostridium acetobutylicum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0004177	molecular_function	aminopeptidase activity
B	0005737	cellular_component	cytoplasm
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity
B	0008270	molecular_function	zinc ion binding
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0004177	molecular_function	aminopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008237	molecular_function	metallopeptidase activity
C	0008270	molecular_function	zinc ion binding
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
D	0004177	molecular_function	aminopeptidase activity
D	0005737	cellular_component	cytoplasm
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008237	molecular_function	metallopeptidase activity
D	0008270	molecular_function	zinc ion binding
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
E	0004177	molecular_function	aminopeptidase activity
E	0005737	cellular_component	cytoplasm
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
E	0008237	molecular_function	metallopeptidase activity
E	0008270	molecular_function	zinc ion binding
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
F	0004177	molecular_function	aminopeptidase activity
F	0005737	cellular_component	cytoplasm
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
F	0008237	molecular_function	metallopeptidase activity
F	0008270	molecular_function	zinc ion binding
F	0016787	molecular_function	hydrolase activity
F	0046872	molecular_function	metal ion binding
G	0004177	molecular_function	aminopeptidase activity
G	0005737	cellular_component	cytoplasm
G	0006508	biological_process	proteolysis
G	0008233	molecular_function	peptidase activity
G	0008237	molecular_function	metallopeptidase activity
G	0008270	molecular_function	zinc ion binding
G	0016787	molecular_function	hydrolase activity
G	0046872	molecular_function	metal ion binding
H	0004177	molecular_function	aminopeptidase activity
H	0005737	cellular_component	cytoplasm
H	0006508	biological_process	proteolysis
H	0008233	molecular_function	peptidase activity
H	0008237	molecular_function	metallopeptidase activity
H	0008270	molecular_function	zinc ion binding
H	0016787	molecular_function	hydrolase activity
H	0046872	molecular_function	metal ion binding
I	0004177	molecular_function	aminopeptidase activity
I	0005737	cellular_component	cytoplasm
I	0006508	biological_process	proteolysis
I	0008233	molecular_function	peptidase activity
I	0008237	molecular_function	metallopeptidase activity
I	0008270	molecular_function	zinc ion binding
I	0016787	molecular_function	hydrolase activity
I	0046872	molecular_function	metal ion binding
J	0004177	molecular_function	aminopeptidase activity
J	0005737	cellular_component	cytoplasm
J	0006508	biological_process	proteolysis
J	0008233	molecular_function	peptidase activity
J	0008237	molecular_function	metallopeptidase activity
J	0008270	molecular_function	zinc ion binding
J	0016787	molecular_function	hydrolase activity
J	0046872	molecular_function	metal ion binding
K	0004177	molecular_function	aminopeptidase activity
K	0005737	cellular_component	cytoplasm
K	0006508	biological_process	proteolysis
K	0008233	molecular_function	peptidase activity
K	0008237	molecular_function	metallopeptidase activity
K	0008270	molecular_function	zinc ion binding
K	0016787	molecular_function	hydrolase activity
K	0046872	molecular_function	metal ion binding
L	0004177	molecular_function	aminopeptidase activity
L	0005737	cellular_component	cytoplasm
L	0006508	biological_process	proteolysis
L	0008233	molecular_function	peptidase activity
L	0008237	molecular_function	metallopeptidase activity
L	0008270	molecular_function	zinc ion binding
L	0016787	molecular_function	hydrolase activity
L	0046872	molecular_function	metal ion binding
M	0004177	molecular_function	aminopeptidase activity
M	0005737	cellular_component	cytoplasm
M	0006508	biological_process	proteolysis
M	0008233	molecular_function	peptidase activity
M	0008237	molecular_function	metallopeptidase activity
M	0008270	molecular_function	zinc ion binding
M	0016787	molecular_function	hydrolase activity
M	0046872	molecular_function	metal ion binding
N	0004177	molecular_function	aminopeptidase activity
N	0005737	cellular_component	cytoplasm
N	0006508	biological_process	proteolysis
N	0008233	molecular_function	peptidase activity
N	0008237	molecular_function	metallopeptidase activity
N	0008270	molecular_function	zinc ion binding
N	0016787	molecular_function	hydrolase activity
N	0046872	molecular_function	metal ion binding
O	0004177	molecular_function	aminopeptidase activity
O	0005737	cellular_component	cytoplasm
O	0006508	biological_process	proteolysis
O	0008233	molecular_function	peptidase activity
O	0008237	molecular_function	metallopeptidase activity
O	0008270	molecular_function	zinc ion binding
O	0016787	molecular_function	hydrolase activity
O	0046872	molecular_function	metal ion binding
P	0004177	molecular_function	aminopeptidase activity
P	0005737	cellular_component	cytoplasm
P	0006508	biological_process	proteolysis
P	0008233	molecular_function	peptidase activity
P	0008237	molecular_function	metallopeptidase activity
P	0008270	molecular_function	zinc ion binding
P	0016787	molecular_function	hydrolase activity
P	0046872	molecular_function	metal ion binding
Q	0004177	molecular_function	aminopeptidase activity
Q	0005737	cellular_component	cytoplasm
Q	0006508	biological_process	proteolysis
Q	0008233	molecular_function	peptidase activity
Q	0008237	molecular_function	metallopeptidase activity
Q	0008270	molecular_function	zinc ion binding
Q	0016787	molecular_function	hydrolase activity
Q	0046872	molecular_function	metal ion binding
R	0004177	molecular_function	aminopeptidase activity
R	0005737	cellular_component	cytoplasm
R	0006508	biological_process	proteolysis
R	0008233	molecular_function	peptidase activity
R	0008237	molecular_function	metallopeptidase activity
R	0008270	molecular_function	zinc ion binding
R	0016787	molecular_function	hydrolase activity
R	0046872	molecular_function	metal ion binding
S	0004177	molecular_function	aminopeptidase activity
S	0005737	cellular_component	cytoplasm
S	0006508	biological_process	proteolysis
S	0008233	molecular_function	peptidase activity
S	0008237	molecular_function	metallopeptidase activity
S	0008270	molecular_function	zinc ion binding
S	0016787	molecular_function	hydrolase activity
S	0046872	molecular_function	metal ion binding
T	0004177	molecular_function	aminopeptidase activity
T	0005737	cellular_component	cytoplasm
T	0006508	biological_process	proteolysis
T	0008233	molecular_function	peptidase activity
T	0008237	molecular_function	metallopeptidase activity
T	0008270	molecular_function	zinc ion binding
T	0016787	molecular_function	hydrolase activity
T	0046872	molecular_function	metal ion binding
U	0004177	molecular_function	aminopeptidase activity
U	0005737	cellular_component	cytoplasm
U	0006508	biological_process	proteolysis
U	0008233	molecular_function	peptidase activity
U	0008237	molecular_function	metallopeptidase activity
U	0008270	molecular_function	zinc ion binding
U	0016787	molecular_function	hydrolase activity
U	0046872	molecular_function	metal ion binding
V	0004177	molecular_function	aminopeptidase activity
V	0005737	cellular_component	cytoplasm
V	0006508	biological_process	proteolysis
V	0008233	molecular_function	peptidase activity
V	0008237	molecular_function	metallopeptidase activity
V	0008270	molecular_function	zinc ion binding
V	0016787	molecular_function	hydrolase activity
V	0046872	molecular_function	metal ion binding
W	0004177	molecular_function	aminopeptidase activity
W	0005737	cellular_component	cytoplasm
W	0006508	biological_process	proteolysis
W	0008233	molecular_function	peptidase activity
W	0008237	molecular_function	metallopeptidase activity
W	0008270	molecular_function	zinc ion binding
W	0016787	molecular_function	hydrolase activity
W	0046872	molecular_function	metal ion binding
X	0004177	molecular_function	aminopeptidase activity
X	0005737	cellular_component	cytoplasm
X	0006508	biological_process	proteolysis
X	0008233	molecular_function	peptidase activity
X	0008237	molecular_function	metallopeptidase activity
X	0008270	molecular_function	zinc ion binding
X	0016787	molecular_function	hydrolase activity
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 6001

Chain	Residue
A	ASP265
A	GLU296
A	MSE440
A	HIS441
A	MN6002
A	HOH6108

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 6002

Chain	Residue
A	GLU296
A	ASP342
A	MN6001
A	HIS105
A	ASP265
A	GLU295

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 6003

Chain	Residue
B	ASP265
B	GLU296
B	MSE440
B	HIS441
B	MN6004

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN B 6004

Chain	Residue
B	HIS105
B	ASP265
B	GLU295
B	GLU296
B	ASP342
B	MN6003

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 6005

Chain	Residue
C	ASP265
C	GLU296
C	MSE440
C	HIS441
C	MN6006

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN C 6006

Chain	Residue
C	HIS105
C	ASP265
C	GLU295
C	GLU296
C	ASP342
C	MN6005
C	HOH6127

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN D 6007

Chain	Residue
D	ASP265
D	GLU296
D	MSE440
D	HIS441
D	MN6008

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN D 6008

Chain	Residue
D	HIS105
D	ASP265
D	GLU295
D	GLU296
D	ASP342
D	MN6007
D	HOH6026

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN E 6009

Chain	Residue
E	ASP265
E	GLU296
E	MSE440
E	HIS441
E	MN6010
E	HOH6203

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN E 6010

Chain	Residue
E	HIS105
E	ASP265
E	GLU295
E	GLU296
E	ASP342
E	MN6009

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN F 6011

Chain	Residue
F	ASP265
F	GLU296
F	MSE440
F	HIS441
F	MN6012
F	HOH6043

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN F 6012

Chain	Residue
F	HIS105
F	ASP265
F	GLU295
F	GLU296
F	ASP342
F	MN6011
F	HOH6021

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN G 6013

Chain	Residue
G	ASP265
G	GLU296
G	MSE440
G	HIS441
G	MN6014
G	HOH6040

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN G 6014

Chain	Residue
G	HIS105
G	ASP265
G	ASP266
G	GLU295
G	GLU296
G	ASP342
G	MN6013

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN H 6015

Chain	Residue
H	ASP265
H	GLU296
H	MSE440
H	HIS441
H	MN6016

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN H 6016

Chain	Residue
H	HIS105
H	ASP265
H	GLU296
H	ASP342
H	MN6015

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN I 6017

Chain	Residue
I	MN6018
I	HOH6115
I	ASP265
I	GLU296
I	MSE440
I	HIS441

site_id	BC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN I 6018

Chain	Residue
I	HIS105
I	ASP265
I	GLU295
I	GLU296
I	ASP342
I	MN6017
I	HOH6115

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN J 6019

Chain	Residue
J	ASP265
J	GLU296
J	MSE440
J	HIS441
J	MN6020
J	HOH6023

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN J 6020

Chain	Residue
J	HIS105
J	ASP265
J	GLU296
J	ASP342
J	MN6019

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN K 6021

Chain	Residue
K	ASP265
K	GLU296
K	MSE440
K	HIS441
K	MN6022

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN K 6022

Chain	Residue
K	HIS105
K	ASP265
K	GLU295
K	GLU296
K	ASP342
K	MN6021

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN L 6023

Chain	Residue
L	ASP265
L	GLU296
L	MSE440
L	HIS441
L	MN6024
L	HOH6116

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN L 6024

Chain	Residue
L	HIS105
L	ASP265
L	GLU295
L	GLU296
L	ASP342
L	MN6023

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN M 6025

Chain	Residue
M	ASP265
M	GLU296
M	MSE440
M	HIS441
M	MN6026
M	HOH6219

site_id	CC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN M 6026

Chain	Residue
M	HIS105
M	ASP265
M	GLU295
M	GLU296
M	ASP342
M	MN6025

site_id	CC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN N 6027

Chain	Residue
N	ASP265
N	GLU296
N	MSE440
N	HIS441
N	MN6028

site_id	DC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN N 6028

Chain	Residue
N	HIS105
N	ASP265
N	GLU295
N	GLU296
N	ASP342
N	MN6027

site_id	DC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN O 6029

Chain	Residue
O	ASP265
O	GLU296
O	MSE440
O	HIS441
O	MN6030
O	HOH6151

site_id	DC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN O 6030

Chain	Residue
O	HIS105
O	ASP265
O	GLU295
O	GLU296
O	ASP342
O	MN6029
O	HOH6151

site_id	DC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN P 6031

Chain	Residue
P	ASP265
P	GLU296
P	MSE440
P	HIS441
P	MN6032
P	HOH6072

site_id	DC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN P 6032

Chain	Residue
P	HIS105
P	ASP265
P	GLU295
P	GLU296
P	ASP342
P	MN6031

site_id	DC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN Q 6033

Chain	Residue
Q	ASP265
Q	GLU296
Q	MSE440
Q	HIS441
Q	MN6034
Q	HOH6056

site_id	DC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN Q 6034

Chain	Residue
Q	HIS105
Q	ASP265
Q	GLU295
Q	GLU296
Q	ASP342
Q	MN6033
Q	HOH6056

site_id	DC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN R 6035

Chain	Residue
R	ASP265
R	GLU296
R	MSE440
R	HIS441
R	MN6036
R	HOH6197

site_id	DC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN R 6036

Chain	Residue
R	HIS105
R	ASP265
R	GLU296
R	ASP342
R	MN6035
R	HOH6197

site_id	EC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN S 6037

Chain	Residue
S	ASP265
S	GLU296
S	MSE440
S	HIS441
S	MN6038
S	HOH6121

site_id	EC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN S 6038

Chain	Residue
S	HIS105
S	ASP265
S	GLU295
S	GLU296
S	ASP342
S	MN6037

site_id	EC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN T 6039

Chain	Residue
T	ASP265
T	GLU296
T	MSE440
T	HIS441
T	MN6040

site_id	EC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN T 6040

Chain	Residue
T	HIS105
T	ASP265
T	GLU295
T	GLU296
T	ASP342
T	MN6039

site_id	EC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN U 6041

Chain	Residue
U	ASP265
U	GLU296
U	MSE440
U	HIS441
U	MN6042
U	HOH6049
U	HOH6087

site_id	EC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN U 6042

Chain	Residue
U	HIS105
U	ASP265
U	GLU295
U	GLU296
U	ASP342
U	MN6041

site_id	EC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN V 6043

Chain	Residue
V	ASP265
V	GLU296
V	MSE440
V	HIS441
V	MN6044
V	HOH6121
V	HOH6264

site_id	EC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MN V 6044

Chain	Residue
V	HIS105
V	ASP265
V	GLU295
V	GLU296
V	ASP342
V	MN6043
V	HOH6264

site_id	EC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN W 6045

Chain	Residue
W	ASP265
W	GLU296
W	MSE440
W	HIS441
W	MN6046
W	HOH6077

site_id	FC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN W 6046

Chain	Residue
W	HIS105
W	ASP265
W	GLU296
W	ASP342
W	MN6045
W	HOH6247

site_id	FC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN X 6047

Chain	Residue
X	ASP265
X	GLU296
X	MSE440
X	HIS441
X	MN6048

site_id	FC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN X 6048

Chain	Residue
X	HIS105
X	ASP265
X	GLU295
X	GLU296
X	ASP342
X	MN6047

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	72
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)