2GLJ
crystal structure of aminopeptidase I from Clostridium acetobutylicum
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004177 | molecular_function | aminopeptidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004177 | molecular_function | aminopeptidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006508 | biological_process | proteolysis |
| C | 0008237 | molecular_function | metallopeptidase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0004177 | molecular_function | aminopeptidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006508 | biological_process | proteolysis |
| D | 0008237 | molecular_function | metallopeptidase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| E | 0004177 | molecular_function | aminopeptidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006508 | biological_process | proteolysis |
| E | 0008237 | molecular_function | metallopeptidase activity |
| E | 0008270 | molecular_function | zinc ion binding |
| F | 0004177 | molecular_function | aminopeptidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006508 | biological_process | proteolysis |
| F | 0008237 | molecular_function | metallopeptidase activity |
| F | 0008270 | molecular_function | zinc ion binding |
| G | 0004177 | molecular_function | aminopeptidase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006508 | biological_process | proteolysis |
| G | 0008237 | molecular_function | metallopeptidase activity |
| G | 0008270 | molecular_function | zinc ion binding |
| H | 0004177 | molecular_function | aminopeptidase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006508 | biological_process | proteolysis |
| H | 0008237 | molecular_function | metallopeptidase activity |
| H | 0008270 | molecular_function | zinc ion binding |
| I | 0004177 | molecular_function | aminopeptidase activity |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0006508 | biological_process | proteolysis |
| I | 0008237 | molecular_function | metallopeptidase activity |
| I | 0008270 | molecular_function | zinc ion binding |
| J | 0004177 | molecular_function | aminopeptidase activity |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0006508 | biological_process | proteolysis |
| J | 0008237 | molecular_function | metallopeptidase activity |
| J | 0008270 | molecular_function | zinc ion binding |
| K | 0004177 | molecular_function | aminopeptidase activity |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0006508 | biological_process | proteolysis |
| K | 0008237 | molecular_function | metallopeptidase activity |
| K | 0008270 | molecular_function | zinc ion binding |
| L | 0004177 | molecular_function | aminopeptidase activity |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0006508 | biological_process | proteolysis |
| L | 0008237 | molecular_function | metallopeptidase activity |
| L | 0008270 | molecular_function | zinc ion binding |
| M | 0004177 | molecular_function | aminopeptidase activity |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0006508 | biological_process | proteolysis |
| M | 0008237 | molecular_function | metallopeptidase activity |
| M | 0008270 | molecular_function | zinc ion binding |
| N | 0004177 | molecular_function | aminopeptidase activity |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0006508 | biological_process | proteolysis |
| N | 0008237 | molecular_function | metallopeptidase activity |
| N | 0008270 | molecular_function | zinc ion binding |
| O | 0004177 | molecular_function | aminopeptidase activity |
| O | 0005737 | cellular_component | cytoplasm |
| O | 0006508 | biological_process | proteolysis |
| O | 0008237 | molecular_function | metallopeptidase activity |
| O | 0008270 | molecular_function | zinc ion binding |
| P | 0004177 | molecular_function | aminopeptidase activity |
| P | 0005737 | cellular_component | cytoplasm |
| P | 0006508 | biological_process | proteolysis |
| P | 0008237 | molecular_function | metallopeptidase activity |
| P | 0008270 | molecular_function | zinc ion binding |
| Q | 0004177 | molecular_function | aminopeptidase activity |
| Q | 0005737 | cellular_component | cytoplasm |
| Q | 0006508 | biological_process | proteolysis |
| Q | 0008237 | molecular_function | metallopeptidase activity |
| Q | 0008270 | molecular_function | zinc ion binding |
| R | 0004177 | molecular_function | aminopeptidase activity |
| R | 0005737 | cellular_component | cytoplasm |
| R | 0006508 | biological_process | proteolysis |
| R | 0008237 | molecular_function | metallopeptidase activity |
| R | 0008270 | molecular_function | zinc ion binding |
| S | 0004177 | molecular_function | aminopeptidase activity |
| S | 0005737 | cellular_component | cytoplasm |
| S | 0006508 | biological_process | proteolysis |
| S | 0008237 | molecular_function | metallopeptidase activity |
| S | 0008270 | molecular_function | zinc ion binding |
| T | 0004177 | molecular_function | aminopeptidase activity |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0006508 | biological_process | proteolysis |
| T | 0008237 | molecular_function | metallopeptidase activity |
| T | 0008270 | molecular_function | zinc ion binding |
| U | 0004177 | molecular_function | aminopeptidase activity |
| U | 0005737 | cellular_component | cytoplasm |
| U | 0006508 | biological_process | proteolysis |
| U | 0008237 | molecular_function | metallopeptidase activity |
| U | 0008270 | molecular_function | zinc ion binding |
| V | 0004177 | molecular_function | aminopeptidase activity |
| V | 0005737 | cellular_component | cytoplasm |
| V | 0006508 | biological_process | proteolysis |
| V | 0008237 | molecular_function | metallopeptidase activity |
| V | 0008270 | molecular_function | zinc ion binding |
| W | 0004177 | molecular_function | aminopeptidase activity |
| W | 0005737 | cellular_component | cytoplasm |
| W | 0006508 | biological_process | proteolysis |
| W | 0008237 | molecular_function | metallopeptidase activity |
| W | 0008270 | molecular_function | zinc ion binding |
| X | 0004177 | molecular_function | aminopeptidase activity |
| X | 0005737 | cellular_component | cytoplasm |
| X | 0006508 | biological_process | proteolysis |
| X | 0008237 | molecular_function | metallopeptidase activity |
| X | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 6001 |
| Chain | Residue |
| A | ASP265 |
| A | GLU296 |
| A | MSE440 |
| A | HIS441 |
| A | MN6002 |
| A | HOH6108 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 6002 |
| Chain | Residue |
| A | GLU296 |
| A | ASP342 |
| A | MN6001 |
| A | HIS105 |
| A | ASP265 |
| A | GLU295 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 6003 |
| Chain | Residue |
| B | ASP265 |
| B | GLU296 |
| B | MSE440 |
| B | HIS441 |
| B | MN6004 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 6004 |
| Chain | Residue |
| B | HIS105 |
| B | ASP265 |
| B | GLU295 |
| B | GLU296 |
| B | ASP342 |
| B | MN6003 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 6005 |
| Chain | Residue |
| C | ASP265 |
| C | GLU296 |
| C | MSE440 |
| C | HIS441 |
| C | MN6006 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN C 6006 |
| Chain | Residue |
| C | HIS105 |
| C | ASP265 |
| C | GLU295 |
| C | GLU296 |
| C | ASP342 |
| C | MN6005 |
| C | HOH6127 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN D 6007 |
| Chain | Residue |
| D | ASP265 |
| D | GLU296 |
| D | MSE440 |
| D | HIS441 |
| D | MN6008 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN D 6008 |
| Chain | Residue |
| D | HIS105 |
| D | ASP265 |
| D | GLU295 |
| D | GLU296 |
| D | ASP342 |
| D | MN6007 |
| D | HOH6026 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN E 6009 |
| Chain | Residue |
| E | ASP265 |
| E | GLU296 |
| E | MSE440 |
| E | HIS441 |
| E | MN6010 |
| E | HOH6203 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN E 6010 |
| Chain | Residue |
| E | HIS105 |
| E | ASP265 |
| E | GLU295 |
| E | GLU296 |
| E | ASP342 |
| E | MN6009 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN F 6011 |
| Chain | Residue |
| F | ASP265 |
| F | GLU296 |
| F | MSE440 |
| F | HIS441 |
| F | MN6012 |
| F | HOH6043 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN F 6012 |
| Chain | Residue |
| F | HIS105 |
| F | ASP265 |
| F | GLU295 |
| F | GLU296 |
| F | ASP342 |
| F | MN6011 |
| F | HOH6021 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN G 6013 |
| Chain | Residue |
| G | ASP265 |
| G | GLU296 |
| G | MSE440 |
| G | HIS441 |
| G | MN6014 |
| G | HOH6040 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN G 6014 |
| Chain | Residue |
| G | HIS105 |
| G | ASP265 |
| G | ASP266 |
| G | GLU295 |
| G | GLU296 |
| G | ASP342 |
| G | MN6013 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN H 6015 |
| Chain | Residue |
| H | ASP265 |
| H | GLU296 |
| H | MSE440 |
| H | HIS441 |
| H | MN6016 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN H 6016 |
| Chain | Residue |
| H | HIS105 |
| H | ASP265 |
| H | GLU296 |
| H | ASP342 |
| H | MN6015 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN I 6017 |
| Chain | Residue |
| I | MN6018 |
| I | HOH6115 |
| I | ASP265 |
| I | GLU296 |
| I | MSE440 |
| I | HIS441 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN I 6018 |
| Chain | Residue |
| I | HIS105 |
| I | ASP265 |
| I | GLU295 |
| I | GLU296 |
| I | ASP342 |
| I | MN6017 |
| I | HOH6115 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN J 6019 |
| Chain | Residue |
| J | ASP265 |
| J | GLU296 |
| J | MSE440 |
| J | HIS441 |
| J | MN6020 |
| J | HOH6023 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN J 6020 |
| Chain | Residue |
| J | HIS105 |
| J | ASP265 |
| J | GLU296 |
| J | ASP342 |
| J | MN6019 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN K 6021 |
| Chain | Residue |
| K | ASP265 |
| K | GLU296 |
| K | MSE440 |
| K | HIS441 |
| K | MN6022 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN K 6022 |
| Chain | Residue |
| K | HIS105 |
| K | ASP265 |
| K | GLU295 |
| K | GLU296 |
| K | ASP342 |
| K | MN6021 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN L 6023 |
| Chain | Residue |
| L | ASP265 |
| L | GLU296 |
| L | MSE440 |
| L | HIS441 |
| L | MN6024 |
| L | HOH6116 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN L 6024 |
| Chain | Residue |
| L | HIS105 |
| L | ASP265 |
| L | GLU295 |
| L | GLU296 |
| L | ASP342 |
| L | MN6023 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN M 6025 |
| Chain | Residue |
| M | ASP265 |
| M | GLU296 |
| M | MSE440 |
| M | HIS441 |
| M | MN6026 |
| M | HOH6219 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN M 6026 |
| Chain | Residue |
| M | HIS105 |
| M | ASP265 |
| M | GLU295 |
| M | GLU296 |
| M | ASP342 |
| M | MN6025 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN N 6027 |
| Chain | Residue |
| N | ASP265 |
| N | GLU296 |
| N | MSE440 |
| N | HIS441 |
| N | MN6028 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN N 6028 |
| Chain | Residue |
| N | HIS105 |
| N | ASP265 |
| N | GLU295 |
| N | GLU296 |
| N | ASP342 |
| N | MN6027 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN O 6029 |
| Chain | Residue |
| O | ASP265 |
| O | GLU296 |
| O | MSE440 |
| O | HIS441 |
| O | MN6030 |
| O | HOH6151 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN O 6030 |
| Chain | Residue |
| O | HIS105 |
| O | ASP265 |
| O | GLU295 |
| O | GLU296 |
| O | ASP342 |
| O | MN6029 |
| O | HOH6151 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN P 6031 |
| Chain | Residue |
| P | ASP265 |
| P | GLU296 |
| P | MSE440 |
| P | HIS441 |
| P | MN6032 |
| P | HOH6072 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN P 6032 |
| Chain | Residue |
| P | HIS105 |
| P | ASP265 |
| P | GLU295 |
| P | GLU296 |
| P | ASP342 |
| P | MN6031 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN Q 6033 |
| Chain | Residue |
| Q | ASP265 |
| Q | GLU296 |
| Q | MSE440 |
| Q | HIS441 |
| Q | MN6034 |
| Q | HOH6056 |
| site_id | DC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN Q 6034 |
| Chain | Residue |
| Q | HIS105 |
| Q | ASP265 |
| Q | GLU295 |
| Q | GLU296 |
| Q | ASP342 |
| Q | MN6033 |
| Q | HOH6056 |
| site_id | DC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN R 6035 |
| Chain | Residue |
| R | ASP265 |
| R | GLU296 |
| R | MSE440 |
| R | HIS441 |
| R | MN6036 |
| R | HOH6197 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN R 6036 |
| Chain | Residue |
| R | HIS105 |
| R | ASP265 |
| R | GLU296 |
| R | ASP342 |
| R | MN6035 |
| R | HOH6197 |
| site_id | EC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN S 6037 |
| Chain | Residue |
| S | ASP265 |
| S | GLU296 |
| S | MSE440 |
| S | HIS441 |
| S | MN6038 |
| S | HOH6121 |
| site_id | EC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN S 6038 |
| Chain | Residue |
| S | HIS105 |
| S | ASP265 |
| S | GLU295 |
| S | GLU296 |
| S | ASP342 |
| S | MN6037 |
| site_id | EC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN T 6039 |
| Chain | Residue |
| T | ASP265 |
| T | GLU296 |
| T | MSE440 |
| T | HIS441 |
| T | MN6040 |
| site_id | EC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN T 6040 |
| Chain | Residue |
| T | HIS105 |
| T | ASP265 |
| T | GLU295 |
| T | GLU296 |
| T | ASP342 |
| T | MN6039 |
| site_id | EC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN U 6041 |
| Chain | Residue |
| U | ASP265 |
| U | GLU296 |
| U | MSE440 |
| U | HIS441 |
| U | MN6042 |
| U | HOH6049 |
| U | HOH6087 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN U 6042 |
| Chain | Residue |
| U | HIS105 |
| U | ASP265 |
| U | GLU295 |
| U | GLU296 |
| U | ASP342 |
| U | MN6041 |
| site_id | EC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN V 6043 |
| Chain | Residue |
| V | ASP265 |
| V | GLU296 |
| V | MSE440 |
| V | HIS441 |
| V | MN6044 |
| V | HOH6121 |
| V | HOH6264 |
| site_id | EC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN V 6044 |
| Chain | Residue |
| V | HIS105 |
| V | ASP265 |
| V | GLU295 |
| V | GLU296 |
| V | ASP342 |
| V | MN6043 |
| V | HOH6264 |
| site_id | EC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN W 6045 |
| Chain | Residue |
| W | ASP265 |
| W | GLU296 |
| W | MSE440 |
| W | HIS441 |
| W | MN6046 |
| W | HOH6077 |
| site_id | FC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN W 6046 |
| Chain | Residue |
| W | HIS105 |
| W | ASP265 |
| W | GLU296 |
| W | ASP342 |
| W | MN6045 |
| W | HOH6247 |
| site_id | FC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN X 6047 |
| Chain | Residue |
| X | ASP265 |
| X | GLU296 |
| X | MSE440 |
| X | HIS441 |
| X | MN6048 |
| site_id | FC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN X 6048 |
| Chain | Residue |
| X | HIS105 |
| X | ASP265 |
| X | GLU295 |
| X | GLU296 |
| X | ASP342 |
| X | MN6047 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 72 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
