Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0006470 | biological_process | protein dephosphorylation |
| A | 0016311 | biological_process | dephosphorylation |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0006470 | biological_process | protein dephosphorylation |
| B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 301 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 306 |
Functional Information from PROSITE/UniProt
| site_id | PS00383 |
| Number of Residues | 11 |
| Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. IHCsaGvgRTG |
| Chain | Residue | Details |
| A | ILE1134-GLY1144 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 257 |
| Details | Domain: {"description":"Tyrosine-protein phosphatase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10044","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | HIS1135 | |
| A | GLU1041 | |
| A | CYS1136 | |
| A | ASP1102 | |
| A | ARG1142 | |
| A | THR1143 | |
| site_id | CSA2 |
| Number of Residues | 6 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | HIS1135 | |
| B | GLU1041 | |
| B | CYS1136 | |
| B | ASP1102 | |
| B | ARG1142 | |
| B | THR1143 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | ARG1142 | |
| A | ASP1102 | |
| A | CYS1136 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | ARG1142 | |
| B | ASP1102 | |
| B | CYS1136 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| A | ARG1142 | |
| A | ASP1102 | |
| A | CYS1136 | |
| A | THR1143 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1ytw |
| Chain | Residue | Details |
| B | ARG1142 | |
| B | ASP1102 | |
| B | CYS1136 | |
| B | THR1143 | |
