2GJD

Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000022	biological_process	mitotic spindle elongation
A	0000166	molecular_function	nucleotide binding
A	0000794	cellular_component	condensed nuclear chromosome
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005694	cellular_component	chromosome
A	0016740	molecular_function	transferase activity
A	0016925	biological_process	protein sumoylation
A	0019789	molecular_function	SUMO transferase activity
A	0051301	biological_process	cell division
A	0061656	molecular_function	SUMO conjugating enzyme activity
B	0000022	biological_process	mitotic spindle elongation
B	0000166	molecular_function	nucleotide binding
B	0000794	cellular_component	condensed nuclear chromosome
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005694	cellular_component	chromosome
B	0016740	molecular_function	transferase activity
B	0016925	biological_process	protein sumoylation
B	0019789	molecular_function	SUMO transferase activity
B	0051301	biological_process	cell division
B	0061656	molecular_function	SUMO conjugating enzyme activity
C	0000022	biological_process	mitotic spindle elongation
C	0000166	molecular_function	nucleotide binding
C	0000794	cellular_component	condensed nuclear chromosome
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0016740	molecular_function	transferase activity
C	0016925	biological_process	protein sumoylation
C	0019789	molecular_function	SUMO transferase activity
C	0051301	biological_process	cell division
C	0061656	molecular_function	SUMO conjugating enzyme activity
D	0000022	biological_process	mitotic spindle elongation
D	0000166	molecular_function	nucleotide binding
D	0000794	cellular_component	condensed nuclear chromosome
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005694	cellular_component	chromosome
D	0016740	molecular_function	transferase activity
D	0016925	biological_process	protein sumoylation
D	0019789	molecular_function	SUMO transferase activity
D	0051301	biological_process	cell division
D	0061656	molecular_function	SUMO conjugating enzyme activity

Functional Information from PROSITE/UniProt

site_id	PS00183
Number of Residues	16
Details	UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNVyps.GtICLsiL

Chain	Residue	Details
A	TYR82-LEU97

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	612
Details	Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10133","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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