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2GF5

Structure of intact FADD (MORT1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0001822biological_processkidney development
A0001916biological_processpositive regulation of T cell mediated cytotoxicity
A0002020molecular_functionprotease binding
A0002821biological_processpositive regulation of adaptive immune response
A0005123molecular_functiondeath receptor binding
A0005164molecular_functiontumor necrosis factor receptor binding
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006915biological_processapoptotic process
A0007165biological_processsignal transduction
A0008625biological_processextrinsic apoptotic signaling pathway via death domain receptors
A0009898cellular_componentcytoplasmic side of plasma membrane
A0030674molecular_functionprotein-macromolecule adaptor activity
A0031264cellular_componentdeath-inducing signaling complex
A0031265cellular_componentCD95 death-inducing signaling complex
A0032729biological_processpositive regulation of type II interferon production
A0032757biological_processpositive regulation of interleukin-8 production
A0032760biological_processpositive regulation of tumor necrosis factor production
A0032813molecular_functiontumor necrosis factor receptor superfamily binding
A0032991cellular_componentprotein-containing complex
A0033077biological_processT cell differentiation in thymus
A0033612molecular_functionreceptor serine/threonine kinase binding
A0035591molecular_functionsignaling adaptor activity
A0035877molecular_functiondeath effector domain binding
A0036462biological_processTRAIL-activated apoptotic signaling pathway
A0042104biological_processpositive regulation of activated T cell proliferation
A0042220biological_processresponse to cocaine
A0042802molecular_functionidentical protein binding
A0042981biological_processregulation of apoptotic process
A0043029biological_processT cell homeostasis
A0043065biological_processpositive regulation of apoptotic process
A0043123biological_processpositive regulation of canonical NF-kappaB signal transduction
A0044297cellular_componentcell body
A0044877molecular_functionprotein-containing complex binding
A0045087biological_processinnate immune response
A0045089biological_processpositive regulation of innate immune response
A0045651biological_processpositive regulation of macrophage differentiation
A0045862biological_processpositive regulation of proteolysis
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0048148biological_processbehavioral response to cocaine
A0048535biological_processlymph node development
A0048536biological_processspleen development
A0048538biological_processthymus development
A0051607biological_processdefense response to virus
A0060340biological_processpositive regulation of type I interferon-mediated signaling pathway
A0060544biological_processregulation of necroptotic process
A0060546biological_processnegative regulation of necroptotic process
A0070236biological_processnegative regulation of activation-induced cell death of T cells
A0071260biological_processcellular response to mechanical stimulus
A0071550biological_processdeath-inducing signaling complex assembly
A0089720molecular_functioncaspase binding
A0097049biological_processmotor neuron apoptotic process
A0097190biological_processapoptotic signaling pathway
A0097191biological_processextrinsic apoptotic signaling pathway
A0097192biological_processextrinsic apoptotic signaling pathway in absence of ligand
A0097202biological_processactivation of cysteine-type endopeptidase activity
A0097342cellular_componentripoptosome
A0097527biological_processnecroptotic signaling pathway
A1900119biological_processpositive regulation of execution phase of apoptosis
A2000454biological_processpositive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation
A2001238biological_processpositive regulation of extrinsic apoptotic signaling pathway
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsCARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:24025841, ECO:0000269|PubMed:28860194, ECO:0000269|PubMed:30979585, ECO:0000305|PubMed:23955153, ECO:0007744|PDB:6ACI
ChainResidueDetails
AARG117

224201

PDB entries from 2024-08-28

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