2GCZ

Solution Structure of alpha-Conotoxin OmIA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0030550	molecular_function	acetylcholine receptor inhibitor activity
A	0035792	cellular_component	host cell postsynaptic membrane
A	0035821	biological_process	modulation of process of another organism
A	0090729	molecular_function	toxin activity
A	0099106	molecular_function	ion channel regulator activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NH2 A 18

Chain	Residue
A	PRO13
A	GLY17

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Functional Information from PROSITE/UniProt

site_id	PS60014
Number of Residues	15
Details	ALPHA_CONOTOXIN Alpha-conotoxin family signature. CCShPACNvnnpHIC

Chain	Residue	Details
A	CYS2-CYS16

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	SITE: Key residue for the high potency for alpha-7 nAChRs => ECO:0000305|PubMed:34955864

Chain	Residue	Details
A	HIS5
A	VAL10
A	ASN11

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Glycine amide => ECO:0000269|PubMed:16678128, ECO:0000269|PubMed:16803900

Chain	Residue	Details
A	GLY17

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