Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
C | 0004252 | molecular_function | serine-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 600 |
Chain | Residue |
A | HOH16 |
B | LYS36 |
B | SER92 |
B | HOH627 |
C | TRP237 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 B 601 |
Chain | Residue |
B | HIS40 |
B | GLU70 |
B | GLN73 |
B | LYS82 |
site_id | AC3 |
Number of Residues | 13 |
Details | BINDING SITE FOR CHAIN D OF TETRAPEPTIDE ADDUCT |
Chain | Residue |
C | LYS175 |
C | SER190 |
C | MET192 |
C | GLY193 |
C | ASP194 |
C | SER195 |
C | SER214 |
C | TRP215 |
C | GLY216 |
C | SER217 |
C | HOH280 |
D | HOH505 |
D | HOH506 |
site_id | BND |
Number of Residues | 9 |
Details | SUBSTRATE BINDING SITE |
Chain | Residue |
C | SER218 |
C | CYS220 |
C | TYR228 |
C | SER190 |
C | CYS191 |
C | MET192 |
C | VAL213 |
C | SER214 |
C | TRP215 |
site_id | CAT |
Number of Residues | 3 |
Details | CATALYTIC CENTER OF THE MOLECULE |
Chain | Residue |
B | HIS57 |
B | ASP102 |
C | SER195 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
Chain | Residue | Details |
B | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV |
Chain | Residue | Details |
C | SER189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
C | SER195 | |
B | ASP102 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
A | NAL * |
A | NAL * |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
A | NAL * |
A | NAL * |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
A | NAL * |
A | NAL * |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
B | ASP102 | |
B | HIS57 | |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
C | SER195 | |
C | GLY193 | |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hja |
Chain | Residue | Details |
C | SER195 | |
C | GLY196 | |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 387 |
Chain | Residue | Details |
C | GLY193 | electrostatic stabiliser |
C | SER195 | covalent catalysis |
C | GLY196 | electrostatic stabiliser |