2GAK
X-ray crystal structure of murine leukocyte-type Core 2 b1,6-N-acetylglucosaminyltransferase (C2GnT-L)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000139 | cellular_component | Golgi membrane |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003829 | molecular_function | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005802 | cellular_component | trans-Golgi network |
| A | 0006486 | biological_process | protein glycosylation |
| A | 0009101 | biological_process | glycoprotein biosynthetic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016268 | biological_process | core 2 O-glycan biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0031985 | cellular_component | Golgi cisterna |
| A | 0032868 | biological_process | response to insulin |
| A | 0048729 | biological_process | tissue morphogenesis |
| A | 0050901 | biological_process | leukocyte tethering or rolling |
| A | 0060352 | biological_process | cell adhesion molecule production |
| A | 0060993 | biological_process | kidney morphogenesis |
| A | 1903238 | biological_process | positive regulation of leukocyte tethering or rolling |
| B | 0000139 | cellular_component | Golgi membrane |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003829 | molecular_function | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005794 | cellular_component | Golgi apparatus |
| B | 0005802 | cellular_component | trans-Golgi network |
| B | 0006486 | biological_process | protein glycosylation |
| B | 0009101 | biological_process | glycoprotein biosynthetic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016268 | biological_process | core 2 O-glycan biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0031985 | cellular_component | Golgi cisterna |
| B | 0032868 | biological_process | response to insulin |
| B | 0048729 | biological_process | tissue morphogenesis |
| B | 0050901 | biological_process | leukocyte tethering or rolling |
| B | 0060352 | biological_process | cell adhesion molecule production |
| B | 0060993 | biological_process | kidney morphogenesis |
| B | 1903238 | biological_process | positive regulation of leukocyte tethering or rolling |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"16829524","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22056345","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3OTK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16829524","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GAM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12954635","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16829524","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22056345","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GAK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3OTK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
