Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2G9T

Crystal structure of the SARS coronavirus nsp10 at 2.1A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0008270	molecular_function	zinc ion binding
A	0019079	biological_process	viral genome replication
B	0003723	molecular_function	RNA binding
B	0008270	molecular_function	zinc ion binding
B	0019079	biological_process	viral genome replication
C	0003723	molecular_function	RNA binding
C	0008270	molecular_function	zinc ion binding
C	0019079	biological_process	viral genome replication
D	0003723	molecular_function	RNA binding
D	0008270	molecular_function	zinc ion binding
D	0019079	biological_process	viral genome replication
E	0003723	molecular_function	RNA binding
E	0008270	molecular_function	zinc ion binding
E	0019079	biological_process	viral genome replication
F	0003723	molecular_function	RNA binding
F	0008270	molecular_function	zinc ion binding
F	0019079	biological_process	viral genome replication
G	0003723	molecular_function	RNA binding
G	0008270	molecular_function	zinc ion binding
G	0019079	biological_process	viral genome replication
H	0003723	molecular_function	RNA binding
H	0008270	molecular_function	zinc ion binding
H	0019079	biological_process	viral genome replication
I	0003723	molecular_function	RNA binding
I	0008270	molecular_function	zinc ion binding
I	0019079	biological_process	viral genome replication
J	0003723	molecular_function	RNA binding
J	0008270	molecular_function	zinc ion binding
J	0019079	biological_process	viral genome replication
K	0003723	molecular_function	RNA binding
K	0008270	molecular_function	zinc ion binding
K	0019079	biological_process	viral genome replication
L	0003723	molecular_function	RNA binding
L	0008270	molecular_function	zinc ion binding
L	0019079	biological_process	viral genome replication
M	0003723	molecular_function	RNA binding
M	0008270	molecular_function	zinc ion binding
M	0019079	biological_process	viral genome replication
N	0003723	molecular_function	RNA binding
N	0008270	molecular_function	zinc ion binding
N	0019079	biological_process	viral genome replication
O	0003723	molecular_function	RNA binding
O	0008270	molecular_function	zinc ion binding
O	0019079	biological_process	viral genome replication
P	0003723	molecular_function	RNA binding
P	0008270	molecular_function	zinc ion binding
P	0019079	biological_process	viral genome replication
Q	0003723	molecular_function	RNA binding
Q	0008270	molecular_function	zinc ion binding
Q	0019079	biological_process	viral genome replication
R	0003723	molecular_function	RNA binding
R	0008270	molecular_function	zinc ion binding
R	0019079	biological_process	viral genome replication
S	0003723	molecular_function	RNA binding
S	0008270	molecular_function	zinc ion binding
S	0019079	biological_process	viral genome replication
T	0003723	molecular_function	RNA binding
T	0008270	molecular_function	zinc ion binding
T	0019079	biological_process	viral genome replication
U	0003723	molecular_function	RNA binding
U	0008270	molecular_function	zinc ion binding
U	0019079	biological_process	viral genome replication
V	0003723	molecular_function	RNA binding
V	0008270	molecular_function	zinc ion binding
V	0019079	biological_process	viral genome replication
W	0003723	molecular_function	RNA binding
W	0008270	molecular_function	zinc ion binding
W	0019079	biological_process	viral genome replication
X	0003723	molecular_function	RNA binding
X	0008270	molecular_function	zinc ion binding
X	0019079	biological_process	viral genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 998

Chain	Residue
A	CYS74
A	CYS77
A	HIS83
A	CYS90

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 999

Chain	Residue
A	CYS117
A	CYS120
A	CYS128
A	HOH1068

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 998

Chain	Residue
B	CYS77
B	HIS83
B	CYS90
B	CYS74

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 999

Chain	Residue
B	CYS117
B	CYS120
B	CYS128
B	HOH1058

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 998

Chain	Residue
C	CYS74
C	CYS77
C	HIS83
C	CYS90

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 999

Chain	Residue
C	CYS117
C	CYS120
C	CYS128
C	HOH1065

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 998

Chain	Residue
D	CYS74
D	CYS77
D	HIS83
D	CYS90

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 999

Chain	Residue
D	CYS117
D	CYS120
D	CYS128
D	HOH1062

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 998

Chain	Residue
E	CYS74
E	CYS77
E	HIS83
E	CYS90

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 999

Chain	Residue
E	CYS117
E	CYS120
E	CYS128
E	HOH1062

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 998

Chain	Residue
F	CYS74
F	CYS77
F	HIS83
F	CYS90

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 999

Chain	Residue
F	CYS117
F	CYS120
F	CYS128
F	HOH1057

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 998

Chain	Residue
G	CYS74
G	CYS77
G	HIS83
G	CYS90

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN G 999

Chain	Residue
G	CYS117
G	CYS120
G	CYS128
G	HOH1064

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN H 998

Chain	Residue
H	CYS74
H	CYS77
H	HIS83
H	CYS90

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN H 999

Chain	Residue
H	CYS117
H	CYS120
H	CYS128
H	SER129
H	HOH1058

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 998

Chain	Residue
I	CYS74
I	CYS77
I	HIS83
I	CYS90

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 999

Chain	Residue
I	CYS117
I	CYS120
I	CYS128
I	HOH1054

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 998

Chain	Residue
J	CYS74
J	CYS77
J	HIS83
J	CYS90

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN J 999

Chain	Residue
J	CYS117
J	CYS120
J	CYS128
J	HOH1072

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN K 998

Chain	Residue
K	CYS74
K	CYS77
K	HIS83
K	CYS90

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN K 999

Chain	Residue
K	CYS117
K	CYS120
K	CYS128
K	SER129
K	HOH1070

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 998

Chain	Residue
L	CYS74
L	CYS77
L	HIS83
L	CYS90

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 999

Chain	Residue
L	CYS117
L	CYS120
L	CYS128
L	HOH1070

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN M 998

Chain	Residue
M	CYS77
M	HIS83
M	CYS90
M	CYS74

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN M 999

Chain	Residue
M	CYS117
M	CYS120
M	CYS128
M	HOH1073

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN N 998

Chain	Residue
N	CYS74
N	CYS77
N	HIS83
N	CYS90

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN N 999

Chain	Residue
N	CYS117
N	CYS120
N	CYS128
N	HOH1050

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN O 998

Chain	Residue
O	CYS74
O	CYS77
O	HIS83
O	CYS90

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN O 999

Chain	Residue
O	CYS117
O	CYS120
O	CYS128
O	SER129
O	HOH1044

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN P 998

Chain	Residue
P	CYS74
P	CYS77
P	HIS83
P	CYS90

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN P 999

Chain	Residue
P	CYS117
P	CYS120
P	CYS128
P	HOH1057

site_id	DC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN Q 998

Chain	Residue
Q	CYS74
Q	CYS77
Q	HIS83
Q	CYS90

site_id	DC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN Q 999

Chain	Residue
Q	CYS117
Q	CYS120
Q	CYS128
Q	HOH1080

site_id	DC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN R 998

Chain	Residue
R	CYS74
R	CYS77
R	HIS83
R	CYS90

site_id	DC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN R 999

Chain	Residue
R	CYS117
R	CYS120
R	CYS128
R	HOH1060

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN S 998

Chain	Residue
S	CYS74
S	CYS77
S	HIS83
S	CYS90

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN S 999

Chain	Residue
S	CYS117
S	CYS120
S	CYS128
S	HOH1066

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN T 998

Chain	Residue
T	CYS74
T	CYS77
T	HIS83
T	CYS90

site_id	EC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN T 999

Chain	Residue
T	CYS117
T	CYS120
T	CYS128
T	HOH1061

site_id	EC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN U 998

Chain	Residue
U	CYS74
U	CYS77
U	HIS83
U	CYS90

site_id	EC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN U 999

Chain	Residue
U	CYS117
U	CYS120
U	CYS128
U	HOH1076

site_id	EC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN V 998

Chain	Residue
V	CYS74
V	CYS77
V	HIS83
V	CYS90

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN V 999

Chain	Residue
V	CYS117
V	CYS120
V	CYS128
V	HOH1048

site_id	EC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN W 998

Chain	Residue
W	CYS74
W	CYS77
W	HIS83
W	CYS90

site_id	FC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN W 999

Chain	Residue
W	CYS117
W	CYS120
W	CYS128
W	SER129
W	HOH1044

site_id	FC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN X 998

Chain	Residue
X	CYS74
X	CYS77
X	HIS83
X	CYS90

site_id	FC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN X 999

Chain	Residue
X	CYS117
X	CYS120
X	CYS128
X	SER129
X	HOH1064

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	168
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01297","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)