2G7M
Crystal structure of B. fragilis N-succinylornithine transcarbamylase P90E mutant complexed with carbamoyl phosphate and N-acetylnorvaline
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| C | 0006520 | biological_process | amino acid metabolic process |
| C | 0006526 | biological_process | arginine biosynthetic process |
| C | 0006591 | biological_process | ornithine metabolic process |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| D | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| D | 0006520 | biological_process | amino acid metabolic process |
| D | 0006526 | biological_process | arginine biosynthetic process |
| D | 0006591 | biological_process | ornithine metabolic process |
| D | 0016597 | molecular_function | amino acid binding |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| E | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| E | 0006520 | biological_process | amino acid metabolic process |
| E | 0006526 | biological_process | arginine biosynthetic process |
| E | 0006591 | biological_process | ornithine metabolic process |
| E | 0016597 | molecular_function | amino acid binding |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| X | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| X | 0006520 | biological_process | amino acid metabolic process |
| X | 0006526 | biological_process | arginine biosynthetic process |
| X | 0006591 | biological_process | ornithine metabolic process |
| X | 0016597 | molecular_function | amino acid binding |
| X | 0016740 | molecular_function | transferase activity |
| X | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| Y | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| Y | 0006520 | biological_process | amino acid metabolic process |
| Y | 0006526 | biological_process | arginine biosynthetic process |
| Y | 0006591 | biological_process | ornithine metabolic process |
| Y | 0016597 | molecular_function | amino acid binding |
| Y | 0016740 | molecular_function | transferase activity |
| Y | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
| Z | 0004585 | molecular_function | ornithine carbamoyltransferase activity |
| Z | 0006520 | biological_process | amino acid metabolic process |
| Z | 0006526 | biological_process | arginine biosynthetic process |
| Z | 0006591 | biological_process | ornithine metabolic process |
| Z | 0016597 | molecular_function | amino acid binding |
| Z | 0016740 | molecular_function | transferase activity |
| Z | 0016743 | molecular_function | carboxyl- or carbamoyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 Y 355 |
| Chain | Residue |
| X | ARG35 |
| Y | ARG35 |
| Z | ARG35 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 356 |
| Chain | Residue |
| C | ARG35 |
| D | ARG35 |
| E | ARG35 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE AN0 X 345 |
| Chain | Residue |
| X | LEU180 |
| X | LYS236 |
| X | LEU275 |
| X | CP346 |
| Z | TRP75 |
| Z | GLU90 |
| X | PHE112 |
| X | GLU142 |
| X | ARG178 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP X 346 |
| Chain | Residue |
| X | SER47 |
| X | LEU48 |
| X | ARG49 |
| X | THR50 |
| X | ARG110 |
| X | HIS147 |
| X | GLN150 |
| X | CYS274 |
| X | LEU275 |
| X | ARG302 |
| X | AN0345 |
| Z | TRP75 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE AN0 Y 445 |
| Chain | Residue |
| X | TRP75 |
| X | GLU90 |
| Y | PHE112 |
| Y | GLU142 |
| Y | ARG178 |
| Y | LEU180 |
| Y | PRO181 |
| Y | LYS236 |
| Y | CP446 |
| Y | HOH488 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP Y 446 |
| Chain | Residue |
| X | TRP75 |
| Y | SER47 |
| Y | LEU48 |
| Y | ARG49 |
| Y | THR50 |
| Y | ARG110 |
| Y | HIS147 |
| Y | GLN150 |
| Y | CYS274 |
| Y | LEU275 |
| Y | ARG302 |
| Y | AN0445 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AN0 Z 545 |
| Chain | Residue |
| Y | TRP75 |
| Y | GLU90 |
| Z | PHE112 |
| Z | GLU142 |
| Z | LEU180 |
| Z | PRO181 |
| Z | LYS236 |
| Z | CP546 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP Z 546 |
| Chain | Residue |
| Y | TRP75 |
| Z | SER47 |
| Z | LEU48 |
| Z | ARG49 |
| Z | THR50 |
| Z | ARG110 |
| Z | HIS147 |
| Z | GLN150 |
| Z | CYS274 |
| Z | LEU275 |
| Z | ARG302 |
| Z | AN0545 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AN0 C 645 |
| Chain | Residue |
| C | ARG110 |
| C | PHE112 |
| C | GLU142 |
| C | PRO181 |
| C | LYS236 |
| C | CP646 |
| E | TRP75 |
| E | GLU90 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP C 646 |
| Chain | Residue |
| C | SER47 |
| C | LEU48 |
| C | ARG49 |
| C | THR50 |
| C | ARG110 |
| C | HIS147 |
| C | GLN150 |
| C | CYS274 |
| C | LEU275 |
| C | ARG302 |
| C | AN0645 |
| E | TRP75 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE AN0 D 745 |
| Chain | Residue |
| C | TRP75 |
| C | GLU90 |
| D | GLU142 |
| D | ARG178 |
| D | VAL184 |
| D | LYS236 |
| D | CP746 |
| site_id | BC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP D 746 |
| Chain | Residue |
| D | ARG49 |
| D | THR50 |
| D | ARG110 |
| D | HIS147 |
| D | GLN150 |
| D | CYS274 |
| D | LEU275 |
| D | ARG302 |
| D | AN0745 |
| C | TRP75 |
| D | SER47 |
| D | LEU48 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE AN0 E 845 |
| Chain | Residue |
| D | TRP75 |
| D | GLU90 |
| E | PHE112 |
| E | GLU142 |
| E | PRO181 |
| E | LYS236 |
| E | CP846 |
| site_id | BC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CP E 846 |
| Chain | Residue |
| D | TRP75 |
| E | SER47 |
| E | LEU48 |
| E | ARG49 |
| E | THR50 |
| E | ARG110 |
| E | HIS147 |
| E | GLN150 |
| E | CYS274 |
| E | LEU275 |
| E | ARG302 |
| E | AN0845 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| X | ARG49 | |
| X | ARG110 | |
| X | HIS147 | |
| X | THR50 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| Y | ARG49 | |
| Y | ARG110 | |
| Y | HIS147 | |
| Y | THR50 |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| Z | ARG49 | |
| Z | ARG110 | |
| Z | HIS147 | |
| Z | THR50 |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| C | ARG49 | |
| C | ARG110 | |
| C | HIS147 | |
| C | THR50 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| D | ARG49 | |
| D | ARG110 | |
| D | HIS147 | |
| D | THR50 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1at1 |
| Chain | Residue | Details |
| E | ARG49 | |
| E | ARG110 | |
| E | HIS147 | |
| E | THR50 |
