Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| A | 0020037 | molecular_function | heme binding |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 860 |
| Chain | Residue |
| A | GLN420 |
| A | TRP587 |
| A | SER657 |
| A | HOH1059 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 861 |
| Chain | Residue |
| B | GLN420 |
| B | TRP587 |
| B | VAL649 |
| B | HOH1041 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| A | CYS331 |
| B | CYS326 |
| B | CYS331 |
| A | CYS326 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM A 750 |
| Chain | Residue |
| A | TRP409 |
| A | ALA412 |
| A | ARG414 |
| A | CYS415 |
| A | PHE584 |
| A | SER585 |
| A | GLY586 |
| A | TRP587 |
| A | GLU592 |
| A | TRP678 |
| A | PHE704 |
| A | TYR706 |
| A | HBI760 |
| A | ARG770 |
| A | CMO920 |
| A | HOH929 |
| A | HOH933 |
| A | HOH956 |
| A | HOH967 |
| A | HOH1101 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HBI A 760 |
| Chain | Residue |
| A | SER334 |
| A | MET336 |
| A | ARG596 |
| A | VAL677 |
| A | TRP678 |
| A | HEM750 |
| A | HOH921 |
| A | HOH933 |
| A | HOH949 |
| A | HOH952 |
| A | HOH1100 |
| B | TRP676 |
| B | PHE691 |
| B | HIS692 |
| B | GLN693 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ARG A 770 |
| Chain | Residue |
| A | GLN478 |
| A | TYR562 |
| A | PRO565 |
| A | TRP587 |
| A | TYR588 |
| A | GLU592 |
| A | ASP597 |
| A | HEM750 |
| A | CMO920 |
| A | HOH928 |
| A | HOH953 |
| A | HOH1103 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CMO A 920 |
| Chain | Residue |
| A | PHE584 |
| A | HEM750 |
| A | ARG770 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM B 750 |
| Chain | Residue |
| B | TRP409 |
| B | ARG414 |
| B | CYS415 |
| B | PHE584 |
| B | SER585 |
| B | TRP587 |
| B | GLU592 |
| B | TRP678 |
| B | PHE704 |
| B | TYR706 |
| B | HBI761 |
| B | ARG771 |
| B | CMO920 |
| B | HOH922 |
| B | HOH925 |
| B | HOH961 |
| B | HOH964 |
| site_id | AC9 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HBI B 761 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| A | GLU694 |
| B | SER334 |
| B | MET336 |
| B | ARG596 |
| B | VAL677 |
| B | TRP678 |
| B | HEM750 |
| B | HOH921 |
| B | HOH925 |
| B | HOH946 |
| B | HOH947 |
| B | HOH1118 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ARG B 771 |
| Chain | Residue |
| B | GLU592 |
| B | ASP597 |
| B | HEM750 |
| B | CMO920 |
| B | HOH933 |
| B | HOH1187 |
| B | GLN478 |
| B | TYR562 |
| B | PRO565 |
| B | TRP587 |
| B | TYR588 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CMO B 920 |
| Chain | Residue |
| B | PHE584 |
| B | HEM750 |
| B | ARG771 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER334 | |
| B | SER334 | |
| B | GLN478 | |
| B | TRP587 | |
| B | TYR588 | |
| B | GLU592 | |
| B | VAL677 | |
| B | TRP678 | |
| B | PHE691 | |
| B | TYR706 | |
| A | GLN478 | |
| A | TRP587 | |
| A | TYR588 | |
| A | GLU592 | |
| A | VAL677 | |
| A | TRP678 | |
| A | PHE691 | |
| A | TYR706 | |
| Chain | Residue | Details |
| A | CYS415 | |
| B | CYS415 | |
