2G5I

Structure of tRNA-Dependent Amidotransferase GatCAB complexed with ADP-AlF4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0006412	biological_process	translation
A	0030956	cellular_component	glutamyl-tRNA(Gln) amidotransferase complex
A	0050567	molecular_function	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
B	0003824	molecular_function	catalytic activity
B	0006412	biological_process	translation
B	0016874	molecular_function	ligase activity
B	0016884	molecular_function	carbon-nitrogen ligase activity, with glutamine as amido-N-donor
B	0050566	molecular_function	asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
B	0050567	molecular_function	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
B	0070681	biological_process	glutaminyl-tRNAGln biosynthesis via transamidation
C	0006412	biological_process	translation
C	0006450	biological_process	regulation of translational fidelity
C	0050566	molecular_function	asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity
C	0050567	molecular_function	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
C	0070681	biological_process	glutaminyl-tRNAGln biosynthesis via transamidation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 501

Chain	Residue
B	HIS12
B	GLU124
B	GLU150
B	HOH603

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site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ADP B 601

Chain	Residue
B	PRO155
B	ASN194
B	SER196
B	PHE205
B	GLY206
B	LYS208
B	HOH609
B	HOH616
B	VAL6
B	ILE7
B	GLU10
B	VAL152
B	SER153

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Functional Information from PROSITE/UniProt

site_id	PS00571
Number of Residues	32
Details	AMIDASES Amidases signature. GGSSGGsAAaVAaglvplSlGsDtGgSIRqPA

Chain	Residue	Details
A	GLY152-ALA183

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site_id	PS01234
Number of Residues	15
Details	GATB Glutamyl-tRNA(Gln) amidotransferase subunit B signature. LNRqgtPLIEIvSeP

Chain	Residue	Details
B	LEU141-PRO155

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"HAMAP-Rule","id":"MF_00120","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"HAMAP-Rule","id":"MF_00120","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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