2G5C
Crystal Structure of Prephenate Dehydrogenase from Aquifex aeolicus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004665 | molecular_function | prephenate dehydrogenase (NADP+) activity |
| A | 0006571 | biological_process | L-tyrosine biosynthetic process |
| A | 0008977 | molecular_function | prephenate dehydrogenase (NAD+) activity |
| A | 0070403 | molecular_function | NAD+ binding |
| B | 0004665 | molecular_function | prephenate dehydrogenase (NADP+) activity |
| B | 0006571 | biological_process | L-tyrosine biosynthetic process |
| B | 0008977 | molecular_function | prephenate dehydrogenase (NAD+) activity |
| B | 0070403 | molecular_function | NAD+ binding |
| C | 0004665 | molecular_function | prephenate dehydrogenase (NADP+) activity |
| C | 0006571 | biological_process | L-tyrosine biosynthetic process |
| C | 0008977 | molecular_function | prephenate dehydrogenase (NAD+) activity |
| C | 0070403 | molecular_function | NAD+ binding |
| D | 0004665 | molecular_function | prephenate dehydrogenase (NADP+) activity |
| D | 0006571 | biological_process | L-tyrosine biosynthetic process |
| D | 0008977 | molecular_function | prephenate dehydrogenase (NAD+) activity |
| D | 0070403 | molecular_function | NAD+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD A 3686 |
| Chain | Residue |
| A | GLY37 |
| A | SER98 |
| A | SER99 |
| A | PRO100 |
| A | VAL101 |
| A | THR103 |
| A | ILE107 |
| A | GLN124 |
| A | SER126 |
| A | ALA150 |
| A | GLY151 |
| A | VAL38 |
| A | GLU153 |
| A | LYS154 |
| A | SER155 |
| A | GLY156 |
| A | HOH3692 |
| A | GLY39 |
| A | PHE40 |
| A | MSE41 |
| A | TYR61 |
| A | ASP62 |
| A | ILE63 |
| A | SER67 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAD B 4686 |
| Chain | Residue |
| B | GLY37 |
| B | VAL38 |
| B | GLY39 |
| B | PHE40 |
| B | MSE41 |
| B | TYR61 |
| B | ASP62 |
| B | ILE63 |
| B | SER67 |
| B | SER98 |
| B | SER99 |
| B | PRO100 |
| B | VAL101 |
| B | ILE107 |
| B | GLN124 |
| B | SER126 |
| B | THR152 |
| B | LYS154 |
| B | SER155 |
| B | GLY156 |
| B | HOH4687 |
| B | HOH4727 |
| site_id | AC3 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAD C 5686 |
| Chain | Residue |
| C | GLY37 |
| C | VAL38 |
| C | GLY39 |
| C | PHE40 |
| C | MSE41 |
| C | TYR61 |
| C | ASP62 |
| C | ILE63 |
| C | ASN64 |
| C | SER67 |
| C | SER98 |
| C | SER99 |
| C | PRO100 |
| C | VAL101 |
| C | THR103 |
| C | ILE107 |
| C | GLN124 |
| C | SER126 |
| C | PRO148 |
| C | ALA150 |
| C | GLY151 |
| C | THR152 |
| C | GLY156 |
| C | MSE258 |
| C | HOH5689 |
| C | HOH5692 |
| C | HOH5800 |
| site_id | AC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE NAD D 6686 |
| Chain | Residue |
| D | HOH6797 |
| D | GLY37 |
| D | VAL38 |
| D | GLY39 |
| D | PHE40 |
| D | MSE41 |
| D | TYR61 |
| D | ASP62 |
| D | ILE63 |
| D | ASN64 |
| D | SER67 |
| D | SER98 |
| D | SER99 |
| D | PRO100 |
| D | VAL101 |
| D | ILE107 |
| D | GLN124 |
| D | SER126 |
| D | ALA150 |
| D | GLY151 |
| D | THR152 |
| D | GLY156 |
| D | MSE258 |
| D | HOH6691 |
| D | HOH6694 |
| D | HOH6717 |
| D | HOH6725 |
