2FYQ

Crystal Structure of the Norwalk Virus Protease

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004197	molecular_function	cysteine-type endopeptidase activity
A	0006508	biological_process	proteolysis

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 401

Chain	Residue
A	HOH621
A	HOH668
A	HOH675
A	HOH689

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 A 403

Chain	Residue
A	HOH483
A	HOH483
A	HOH500
A	HOH612
A	HOH612
A	HIS50
A	GLN57
A	GLN57
A	ARG59
A	ARG59

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 402

Chain	Residue
A	LYS63
A	PRO66
A	HOH467
A	HOH652

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"description":"For 3CLpro activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00870","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16641296","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23365454","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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