2FWR
Structure of Archaeoglobus Fulgidis XPB
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006281 | biological_process | DNA repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0043138 | molecular_function | 3'-5' DNA helicase activity |
| A | 0120545 | molecular_function | nucleic acid conformation isomerase activity |
| A | 0140097 | molecular_function | catalytic activity, acting on DNA |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006281 | biological_process | DNA repair |
| B | 0006974 | biological_process | DNA damage response |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0043138 | molecular_function | 3'-5' DNA helicase activity |
| B | 0120545 | molecular_function | nucleic acid conformation isomerase activity |
| B | 0140097 | molecular_function | catalytic activity, acting on DNA |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004386 | molecular_function | helicase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006281 | biological_process | DNA repair |
| C | 0006974 | biological_process | DNA damage response |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0043138 | molecular_function | 3'-5' DNA helicase activity |
| C | 0120545 | molecular_function | nucleic acid conformation isomerase activity |
| C | 0140097 | molecular_function | catalytic activity, acting on DNA |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0004386 | molecular_function | helicase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006281 | biological_process | DNA repair |
| D | 0006974 | biological_process | DNA damage response |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0043138 | molecular_function | 3'-5' DNA helicase activity |
| D | 0120545 | molecular_function | nucleic acid conformation isomerase activity |
| D | 0140097 | molecular_function | catalytic activity, acting on DNA |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 4001 |
| Chain | Residue |
| A | GLY118 |
| A | SER119 |
| A | GLY120 |
| A | LYS121 |
| A | THR122 |
| A | HOH2052 |
| A | HOH2139 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 4002 |
| Chain | Residue |
| B | GLY120 |
| B | LYS121 |
| B | THR122 |
| B | HOH2256 |
| B | GLY118 |
| B | SER119 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 C 4003 |
| Chain | Residue |
| C | PRO116 |
| C | GLY118 |
| C | SER119 |
| C | GLY120 |
| C | LYS121 |
| C | THR122 |
| C | HOH2458 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 D 4004 |
| Chain | Residue |
| D | GLY118 |
| D | SER119 |
| D | GLY120 |
| D | LYS121 |
| D | THR122 |
| D | HOH2224 |
| D | HOH2271 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 D 4005 |
| Chain | Residue |
| A | ASP180 |
| A | TYR183 |
| A | SER208 |
| A | HOH2734 |
| D | LEU143 |
| D | ALA144 |
| D | GLU147 |
| D | ARG167 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 D 4006 |
| Chain | Residue |
| A | GLU147 |
| A | ARG167 |
| D | ASP180 |
| D | TYR183 |
| D | SER208 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 B 4007 |
| Chain | Residue |
| B | LEU143 |
| B | GLU147 |
| B | ARG167 |
| C | TYR183 |
| C | SER208 |
| C | TYR209 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 4008 |
| Chain | Residue |
| B | ASP180 |
| B | TYR183 |
| B | SER208 |
| C | GLU147 |
| C | ARG167 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IPA A 6001 |
| Chain | Residue |
| A | HIS203 |
| A | ALA206 |
| A | ARG230 |
| D | GLN148 |
| D | HOH2242 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IPA A 6002 |
| Chain | Residue |
| A | GLU207 |
| A | ARG234 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IPA A 6003 |
| Chain | Residue |
| A | ASP81 |
| B | GLU170 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 576 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Region: {"description":"Flexible hinge region","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 61 |
| Details | Region: {"description":"ThM region","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Motif: {"description":"DEAH box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Motif: {"description":"RED motif","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Site: {"description":"Wedge residue","evidences":[{"source":"UniProtKB","id":"Q970I2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 59 |
| Details | Region: {"description":"DRD domain","evidences":[{"source":"PubMed","id":"16600867","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
