Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2FWR

Structure of Archaeoglobus Fulgidis XPB

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0006281	biological_process	DNA repair
A	0006367	biological_process	transcription initiation at RNA polymerase II promoter
A	0016787	molecular_function	hydrolase activity
A	0016853	molecular_function	isomerase activity
A	0032508	biological_process	DNA duplex unwinding
A	0043138	molecular_function	3'-5' DNA helicase activity
A	0071840	biological_process	cellular component organization or biogenesis
A	0097550	cellular_component	transcription preinitiation complex
A	0140097	molecular_function	catalytic activity, acting on DNA
B	0003677	molecular_function	DNA binding
B	0004386	molecular_function	helicase activity
B	0005524	molecular_function	ATP binding
B	0006281	biological_process	DNA repair
B	0006367	biological_process	transcription initiation at RNA polymerase II promoter
B	0016787	molecular_function	hydrolase activity
B	0016853	molecular_function	isomerase activity
B	0032508	biological_process	DNA duplex unwinding
B	0043138	molecular_function	3'-5' DNA helicase activity
B	0071840	biological_process	cellular component organization or biogenesis
B	0097550	cellular_component	transcription preinitiation complex
B	0140097	molecular_function	catalytic activity, acting on DNA
C	0003677	molecular_function	DNA binding
C	0004386	molecular_function	helicase activity
C	0005524	molecular_function	ATP binding
C	0006281	biological_process	DNA repair
C	0006367	biological_process	transcription initiation at RNA polymerase II promoter
C	0016787	molecular_function	hydrolase activity
C	0016853	molecular_function	isomerase activity
C	0032508	biological_process	DNA duplex unwinding
C	0043138	molecular_function	3'-5' DNA helicase activity
C	0071840	biological_process	cellular component organization or biogenesis
C	0097550	cellular_component	transcription preinitiation complex
C	0140097	molecular_function	catalytic activity, acting on DNA
D	0003677	molecular_function	DNA binding
D	0004386	molecular_function	helicase activity
D	0005524	molecular_function	ATP binding
D	0006281	biological_process	DNA repair
D	0006367	biological_process	transcription initiation at RNA polymerase II promoter
D	0016787	molecular_function	hydrolase activity
D	0016853	molecular_function	isomerase activity
D	0032508	biological_process	DNA duplex unwinding
D	0043138	molecular_function	3'-5' DNA helicase activity
D	0071840	biological_process	cellular component organization or biogenesis
D	0097550	cellular_component	transcription preinitiation complex
D	0140097	molecular_function	catalytic activity, acting on DNA

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 4001

Chain	Residue
A	GLY118
A	SER119
A	GLY120
A	LYS121
A	THR122
A	HOH2052
A	HOH2139

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 B 4002

Chain	Residue
B	GLY120
B	LYS121
B	THR122
B	HOH2256
B	GLY118
B	SER119

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 C 4003

Chain	Residue
C	PRO116
C	GLY118
C	SER119
C	GLY120
C	LYS121
C	THR122
C	HOH2458

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 D 4004

Chain	Residue
D	GLY118
D	SER119
D	GLY120
D	LYS121
D	THR122
D	HOH2224
D	HOH2271

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 D 4005

Chain	Residue
A	ASP180
A	TYR183
A	SER208
A	HOH2734
D	LEU143
D	ALA144
D	GLU147
D	ARG167

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 D 4006

Chain	Residue
A	GLU147
A	ARG167
D	ASP180
D	TYR183
D	SER208

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 B 4007

Chain	Residue
B	LEU143
B	GLU147
B	ARG167
C	TYR183
C	SER208
C	TYR209

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 B 4008

Chain	Residue
B	ASP180
B	TYR183
B	SER208
C	GLU147
C	ARG167

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE IPA A 6001

Chain	Residue
A	HIS203
A	ALA206
A	ARG230
D	GLN148
D	HOH2242

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA A 6002

Chain	Residue
A	GLU207
A	ARG234

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IPA A 6003

Chain	Residue
A	ASP81
B	GLU170

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255\|PROSITE-ProRule:PRU00541

Chain	Residue	Details
A	LEU115
B	LEU115
C	LEU115
D	LEU115

site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Wedge residue => ECO:0000250\|UniProtKB:Q970I2

Chain	Residue	Details
A	PHE303
B	PHE303
C	PHE303
D	PHE303

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)