Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CRL A 999 |
| Chain | Residue |
| A | GLN19 |
| A | GLY133 |
| A | VAL157 |
| A | ASN158 |
| A | HOH9288 |
| A | GLY23 |
| A | CYS25 |
| A | TRP26 |
| A | GLY59 |
| A | ASN64 |
| A | GLY65 |
| A | GLY66 |
| A | PHE67 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CRL B 998 |
| Chain | Residue |
| A | HOH9346 |
| B | GLN19 |
| B | GLY23 |
| B | CYS25 |
| B | TRP26 |
| B | LYS61 |
| B | ASN64 |
| B | GLY65 |
| B | GLY66 |
| B | PHE67 |
| B | GLY133 |
| B | VAL157 |
| B | ASN158 |
| B | HOH9377 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGACWAfSA |
| Chain | Residue | Details |
| A | GLN19-ALA30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHGVLVVGYG |
| Chain | Residue | Details |
| A | VAL157-GLY173 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWghnFGeeGYIrM |
| Chain | Residue | Details |
| A | TYR6174-MET199 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | TRP26 | |
| A | GLY160 | |
| A | SER176 | |
| B | TRP26 | |
| B | GLY160 | |
| B | SER176 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | ASN175 | |
| A | CYS25 | |
| A | HIS159 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | ASN175 | |
| B | CYS25 | |
| B | HIS159 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | GLN19 | |
| A | CYS25 | |
| A | HIS159 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | GLN19 | |
| B | CYS25 | |
| B | HIS159 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | ASN175 | |
| A | GLN19 | |
| A | HIS159 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | ASN175 | |
| B | GLN19 | |
| B | HIS159 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| A | GLY20 | electrostatic stabiliser |
| A | TRP26 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | GLY160 | proton acceptor, proton donor |
| A | SER176 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| B | GLY20 | electrostatic stabiliser |
| B | TRP26 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | GLY160 | proton acceptor, proton donor |
| B | SER176 | electrostatic stabiliser |
