Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008800 | molecular_function | beta-lactamase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0017001 | biological_process | antibiotic catabolic process |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | HIS116 |
| A | HIS118 |
| A | HIS196 |
| A | MP21410 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 402 |
| Chain | Residue |
| A | ASP120 |
| A | HIS121 |
| A | HIS263 |
| A | MP21410 |
| A | HOH1641 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | HIS116 |
| B | HIS118 |
| B | HIS196 |
| B | MP22410 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 402 |
| Chain | Residue |
| B | ASP120 |
| B | HIS121 |
| B | HIS263 |
| B | MP22410 |
| B | HOH2580 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1 |
| Chain | Residue |
| B | ARG172 |
| B | VAL179 |
| B | ILE180 |
| B | THR181 |
| B | HOH2479 |
| B | HOH2573 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2 |
| Chain | Residue |
| A | ARG172 |
| A | VAL179 |
| A | ILE180 |
| A | THR181 |
| A | HOH1587 |
| A | HOH1687 |
| A | HOH1716 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 3 |
| Chain | Residue |
| A | ARG252 |
| A | LYS297 |
| A | HOH1518 |
| A | HOH1528 |
| B | ARG209 |
| B | ALA275 |
| B | ARG276 |
| B | ALA289 |
| B | GLY290 |
| B | ALA291 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4 |
| Chain | Residue |
| A | ARG209 |
| A | ALA275 |
| A | ARG276 |
| A | ALA289 |
| A | GLY290 |
| A | ALA291 |
| A | HOH1543 |
| A | HOH1563 |
| B | ARG252 |
| B | LYS297 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 5 |
| Chain | Residue |
| A | ARG252 |
| A | HOH1721 |
| B | ARG209 |
| B | ASN210 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 6 |
| Chain | Residue |
| A | ARG102 |
| A | ASN210 |
| A | HOH1494 |
| A | HOH1549 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 7 |
| Chain | Residue |
| B | ARG102 |
| B | GLY211 |
| B | HOH2602 |
| site_id | BC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE MP2 A 1410 |
| Chain | Residue |
| A | TYR33 |
| A | TRP39 |
| A | ASP120 |
| A | PHE156 |
| A | GLY161 |
| A | ILE162 |
| A | HIS196 |
| A | SER225 |
| A | PRO227 |
| A | HIS263 |
| A | ZN401 |
| A | ZN402 |
| A | HOH1630 |
| A | HOH1641 |
| A | HOH1673 |
| site_id | BC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE MP2 B 2410 |
| Chain | Residue |
| B | TYR33 |
| B | TRP39 |
| B | ASP120 |
| B | PHE156 |
| B | GLY161 |
| B | HIS196 |
| B | SER225 |
| B | ZN401 |
| B | ZN402 |
| B | HOH2508 |
| B | HOH2580 |
| B | HOH2587 |
| B | HOH2590 |
| B | HOH2616 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 8 |
| Chain | Residue |
| A | HOH1655 |
| B | ARG276 |
| A | PHE248 |
| A | ALA249 |
| A | ALA300 |
| A | ASP301 |
| A | GLU304 |
| A | HOH1500 |
| A | HOH1603 |
| A | HOH1633 |
| site_id | BC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 9 |
| Chain | Residue |
| A | ARG276 |
| B | ALA249 |
| B | ARG252 |
| B | ALA300 |
| B | ASP301 |
| B | GLU304 |
| B | HOH2490 |
| B | HOH2577 |
| B | HOH2662 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 10 |
| Chain | Residue |
| A | ARG130 |
| A | HOH1480 |
| B | ARG148 |
| B | ASP152 |
| B | ASP171 |
| B | ARG172 |
| B | ILE173 |
| B | HOH2531 |
| B | HOH2571 |
| B | HOH2677 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 11 |
| Chain | Residue |
| A | HOH1470 |
| B | PRO166 |
| B | ALA168 |
| B | ASN169 |
| B | HOH2536 |
Functional Information from PROSITE/UniProt
| site_id | PS00743 |
| Number of Residues | 21 |
| Details | BETA_LACTAMASE_B_1 Beta-lactamases class B signature 1. LlSHaHADhaGPvaelkrrtG |
| Chain | Residue | Details |
| A | LEU113-GLY133 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS116 | |
| B | HIS196 | |
| A | HIS118 | |
| A | ASP120 | |
| A | HIS121 | |
| A | HIS196 | |
| B | HIS116 | |
| B | HIS118 | |
| B | ASP120 | |
| B | HIS121 | |
| Chain | Residue | Details |
| A | ASP220 | |
| B | ASP220 | |
| Chain | Residue | Details |
| A | HIS263 | |
| B | HIS263 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qh5 |
| Chain | Residue | Details |
| A | ASP120 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qh5 |
| Chain | Residue | Details |
| B | ASP120 | |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 258 |
| Chain | Residue | Details |
| A | HIS116 | metal ligand |
| A | HIS118 | metal ligand |
| A | ASP120 | metal ligand |
| A | HIS121 | metal ligand |
| A | HIS196 | metal ligand |
| A | TYR229 | electrostatic stabiliser, hydrogen bond donor |
| A | HIS263 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 7 |
| Details | M-CSA 258 |
| Chain | Residue | Details |
| B | HIS116 | metal ligand |
| B | HIS118 | metal ligand |
| B | ASP120 | metal ligand |
| B | HIS121 | metal ligand |
| B | HIS196 | metal ligand |
| B | TYR229 | electrostatic stabiliser, hydrogen bond donor |
| B | HIS263 | metal ligand |
