2FRX

Crystal structure of YebU, a m5C RNA methyltransferase from E.coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001510	biological_process	RNA methylation
A	0003723	molecular_function	RNA binding
A	0005737	cellular_component	cytoplasm
A	0006364	biological_process	rRNA processing
A	0006396	biological_process	RNA processing
A	0008168	molecular_function	methyltransferase activity
A	0008173	molecular_function	RNA methyltransferase activity
A	0008649	molecular_function	rRNA methyltransferase activity
A	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
A	0009383	molecular_function	rRNA (cytosine-C5-)-methyltransferase activity
A	0016434	molecular_function	rRNA (cytosine) methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0031167	biological_process	rRNA methylation
A	0032259	biological_process	methylation
A	0070475	biological_process	rRNA base methylation
B	0001510	biological_process	RNA methylation
B	0003723	molecular_function	RNA binding
B	0005737	cellular_component	cytoplasm
B	0006364	biological_process	rRNA processing
B	0006396	biological_process	RNA processing
B	0008168	molecular_function	methyltransferase activity
B	0008173	molecular_function	RNA methyltransferase activity
B	0008649	molecular_function	rRNA methyltransferase activity
B	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
B	0009383	molecular_function	rRNA (cytosine-C5-)-methyltransferase activity
B	0016434	molecular_function	rRNA (cytosine) methyltransferase activity
B	0016740	molecular_function	transferase activity
B	0031167	biological_process	rRNA methylation
B	0032259	biological_process	methylation
B	0070475	biological_process	rRNA base methylation
C	0001510	biological_process	RNA methylation
C	0003723	molecular_function	RNA binding
C	0005737	cellular_component	cytoplasm
C	0006364	biological_process	rRNA processing
C	0006396	biological_process	RNA processing
C	0008168	molecular_function	methyltransferase activity
C	0008173	molecular_function	RNA methyltransferase activity
C	0008649	molecular_function	rRNA methyltransferase activity
C	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
C	0009383	molecular_function	rRNA (cytosine-C5-)-methyltransferase activity
C	0016434	molecular_function	rRNA (cytosine) methyltransferase activity
C	0016740	molecular_function	transferase activity
C	0031167	biological_process	rRNA methylation
C	0032259	biological_process	methylation
C	0070475	biological_process	rRNA base methylation
D	0001510	biological_process	RNA methylation
D	0003723	molecular_function	RNA binding
D	0005737	cellular_component	cytoplasm
D	0006364	biological_process	rRNA processing
D	0006396	biological_process	RNA processing
D	0008168	molecular_function	methyltransferase activity
D	0008173	molecular_function	RNA methyltransferase activity
D	0008649	molecular_function	rRNA methyltransferase activity
D	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
D	0009383	molecular_function	rRNA (cytosine-C5-)-methyltransferase activity
D	0016434	molecular_function	rRNA (cytosine) methyltransferase activity
D	0016740	molecular_function	transferase activity
D	0031167	biological_process	rRNA methylation
D	0032259	biological_process	methylation
D	0070475	biological_process	rRNA base methylation

Functional Information from PROSITE/UniProt

site_id	PS01153
Number of Residues	12
Details	NOL1_NOP2_SUN NOL1/NOP2/sun family signature. FDAILlDAPCSG

Chain	Residue	Details
A	PHE188-GLY199

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000250

Chain	Residue	Details
A	CYS247
B	CYS247
C	CYS247
D	CYS247

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ALA125
C	GLU149
C	ASP176
C	ASP194
D	ALA125
D	GLU149
D	ASP176
D	ASP194
A	GLU149
A	ASP176
A	ASP194
B	ALA125
B	GLU149
B	ASP176
B	ASP194
C	ALA125

---