2FPQ
Crystal Structure of Botulinum Neurotoxin Type D Light Chain
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 500 |
| Chain | Residue |
| A | HIS229 |
| A | HIS233 |
| A | GLU269 |
| A | HOH674 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 501 |
| Chain | Residue |
| A | ILE415 |
| A | ASN418 |
| A | LEU421 |
| A | HOH628 |
| A | HOH659 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. ALMHELTHSL |
| Chain | Residue | Details |
| A | ALA226-LEU235 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16519520","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26324071","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2FPQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5BQM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1i1e |
| Chain | Residue | Details |
| A | TYR375 | |
| A | ARG372 | |
| A | GLU269 |
