2FOL
Crystal structure of human RAB1A in complex with GDP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 202 |
| Chain | Residue |
| A | SER22 |
| A | GDP201 |
| A | HOH301 |
| A | HOH302 |
| A | HOH306 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE GDP A 201 |
| Chain | Residue |
| A | GLY20 |
| A | LYS21 |
| A | SER22 |
| A | CYS23 |
| A | TYR33 |
| A | GLU35 |
| A | ASN121 |
| A | LYS122 |
| A | ASP124 |
| A | LEU125 |
| A | SER151 |
| A | ALA152 |
| A | LYS153 |
| A | MG202 |
| A | HOH301 |
| A | HOH302 |
| A | HOH306 |
| A | ASP16 |
| A | SER17 |
| A | GLY18 |
| A | VAL19 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 401 |
| Chain | Residue |
| A | ASP92 |
| A | ASP92 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE UNX A 402 |
| Chain | Residue |
| A | GLY42 |
| A | VAL43 |
| A | ALA81 |
| A | HIS82 |
| A | SER111 |
| A | ARG172 |
Functional Information from PROSITE/UniProt
| site_id | PS00675 |
| Number of Residues | 14 |
| Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKscL |
| Chain | Residue | Details |
| A | LEU11-LEU24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22416225, ECO:0000269|PubMed:22939626, ECO:0000269|PubMed:23588383, ECO:0000269|PubMed:23821544, ECO:0007744|PDB:2FOL, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL, ECO:0007744|PDB:4FMB, ECO:0007744|PDB:4FMC, ECO:0007744|PDB:4FMD, ECO:0007744|PDB:4FME, ECO:0007744|PDB:4IRU, ECO:0007744|PDB:4JVS |
| Chain | Residue | Details |
| A | ASP16 | |
| A | LYS122 | |
| A | ALA152 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22416225, ECO:0000269|PubMed:22939626, ECO:0000269|PubMed:23588383, ECO:0000269|PubMed:23821544, ECO:0007744|PDB:2FOL, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL, ECO:0007744|PDB:4FMC, ECO:0007744|PDB:4FME, ECO:0007744|PDB:4IRU, ECO:0007744|PDB:4JVS |
| Chain | Residue | Details |
| A | THR34 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3TKL |
| Chain | Residue | Details |
| A | THR64 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-(2-cholinephosphoryl)serine => ECO:0000269|PubMed:21822290, ECO:0000269|PubMed:22158903 |
| Chain | Residue | Details |
| A | TYR77 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32504010 |
| Chain | Residue | Details |
| A | PHE70 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32504010, ECO:0000269|PubMed:32974215 |
| Chain | Residue | Details |
| A | THR72 | |
| A | GLY80 | |
| A | TYR109 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P51153 |
| Chain | Residue | Details |
| A | ILE47 | |
| A | LEU59 |
