2FKB
Crystal structure of a putative enzyme (possible Nudix hydrolase) from Escherichia Coli K12
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016817 | molecular_function | hydrolase activity, acting on acid anhydrides |
| A | 0016818 | molecular_function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016817 | molecular_function | hydrolase activity, acting on acid anhydrides |
| B | 0016818 | molecular_function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016817 | molecular_function | hydrolase activity, acting on acid anhydrides |
| C | 0016818 | molecular_function | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | HIS45 |
| A | GLY47 |
| A | MSE48 |
| A | GLY49 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | LYS60 |
| A | ASP61 |
| A | HOH1034 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | PHE100 |
| A | HOH1015 |
| A | HOH1016 |
| A | HOH1050 |
| C | HIS125 |
| C | GLY126 |
| A | ARG86 |
| A | PRO99 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 404 |
| Chain | Residue |
| C | HIS45 |
| C | GLY47 |
| C | MSE48 |
| C | GLY49 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 405 |
| Chain | Residue |
| A | HIS125 |
| C | ARG86 |
| C | PRO99 |
| C | PHE100 |
| C | HOH928 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 406 |
| Chain | Residue |
| B | ARG38 |
| B | HOH936 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 801 |
| Chain | Residue |
| B | HIS45 |
| B | GLY47 |
| B | MSE48 |
| B | GLY49 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 802 |
| Chain | Residue |
| A | ALA23 |
| A | HOH913 |
| B | TRP140 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 803 |
| Chain | Residue |
| B | ARG86 |
| B | PRO99 |
| B | PHE100 |
| B | HIS125 |
| B | HOH964 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT C 804 |
| Chain | Residue |
| B | ALA23 |
| B | HOH935 |
| C | TRP140 |
| C | HOH983 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 910 |
| Chain | Residue |
| A | GLU88 |
| A | GOL904 |
| A | HOH957 |
| A | HOH1035 |
| A | HOH1041 |
| site_id | BC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 900 |
| Chain | Residue |
| B | ARG27 |
| B | ARG31 |
| B | ARG56 |
| B | LYS60 |
| B | ASP61 |
| B | VAL74 |
| B | GLU88 |
| B | HOH910 |
| B | HOH911 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 901 |
| Chain | Residue |
| A | HIS45 |
| A | HIS103 |
| A | SER121 |
| A | CYS122 |
| A | ASN168 |
| A | HOH996 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 902 |
| Chain | Residue |
| A | ASN16 |
| A | GLU17 |
| A | ARG36 |
| A | HOH1048 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 903 |
| Chain | Residue |
| A | GLU20 |
| A | VAL21 |
| A | ARG38 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 904 |
| Chain | Residue |
| A | ARG27 |
| A | ARG56 |
| A | LYS60 |
| A | GLY73 |
| A | VAL74 |
| A | MG910 |
| A | HOH1034 |
| A | HOH1041 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 905 |
| Chain | Residue |
| C | HIS45 |
| C | ALA101 |
| C | HIS103 |
| C | SER121 |
| C | CYS122 |
| C | ASN168 |
| C | HOH957 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 906 |
| Chain | Residue |
| C | VAL21 |
| C | ARG38 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 907 |
| Chain | Residue |
| C | ARG27 |
| C | ARG31 |
| C | ARG56 |
| C | LYS60 |
| C | GLY73 |
| C | VAL74 |
| C | HOH944 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 908 |
| Chain | Residue |
| C | ASN16 |
| C | GLU17 |
| C | ILE22 |
| C | ARG36 |
| C | HOH981 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 66 |
| Details | Motif: {"description":"Nudix box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of a putative enzyme (possible nudix hydrolase) from Escherichia coli K12.","authoringGroup":["Midwest center for structural genomics (MCSG)"]}},{"source":"PDB","id":"2FKB","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
