2FHN

Avidin related protein AVR4 (C122S, K109I mutant) in complex with BNA

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0005576	cellular_component	extracellular region
X	0009374	molecular_function	biotin binding
Y	0005576	cellular_component	extracellular region
Y	0009374	molecular_function	biotin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE BNI X 501

Chain	Residue
X	ASN12
X	THR75
X	TRP95
X	SER99
X	ARG112
X	ASN116
Y	TRP308
X	SER16
X	TYR33
X	THR35
X	VAL37
X	ALA38
X	ASP39
X	TRP68
X	SER73

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE BNI Y 502

Chain	Residue
X	TRP108
Y	ASN212
Y	LEU214
Y	SER216
Y	TYR233
Y	THR235
Y	VAL237
Y	ALA238
Y	ASP239
Y	TRP268
Y	SER273
Y	THR275
Y	TRP295
Y	SER299
Y	ARG312
Y	ASN316

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT Y 901

Chain	Residue
X	GLY42
Y	HIS267
Y	ASN269
Y	HOH935

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FMT Y 902

Chain	Residue
X	HIS67
X	HOH927
X	HOH930
Y	HIS254
Y	LYS255
Y	ARG256

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FMT X 903

Chain	Residue
X	HIS54
X	LYS55
X	ARG56
X	HOH954
Y	HIS267
Y	HOH929
Y	HOH936

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FMT Y 904

Chain	Residue
Y	VAL301
Y	ASN302
Y	TYR306
Y	HOH992
Y	HOH1007

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FMT Y 905

Chain	Residue
X	GLN59
X	PHE82
X	ILE83
Y	ASP303
Y	ILE304
Y	HOH964
Y	HOH978
Y	HOH997

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FMT Y 906

Chain	Residue
Y	THR211
Y	ASN213
Y	ASN317
Y	THR319

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Functional Information from PROSITE/UniProt

site_id	PS00577
Number of Residues	15
Details	AVIDIN_1 Avidin-like domain signature. YdwIAtrVGyNnFTR

Chain	Residue	Details
X	TYR106-ARG120

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	BINDING: BINDING => ECO:0000269|PubMed:15858262, ECO:0007744|PDB:1Y52, ECO:0007744|PDB:1Y55

Chain	Residue	Details
X	ASN12
Y	TYR233
Y	THR235
Y	ASP239
Y	SER271
Y	ASN316
X	SER16
X	TYR33
X	THR35
X	ASP39
X	SER71
X	ASN116
Y	ASN212
Y	SER216

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15858262, ECO:0007744|PDB:1Y52

Chain	Residue	Details
X	ASN43
X	ASN117
Y	ASN243
Y	ASN317

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
X	ASN69
Y	ASN269

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