2FHK
Crystal structure of formylmethanofuran: tetrahydromethanopterin formyltransferase in complex with its coenzymes
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0015948 | biological_process | methanogenesis |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| A | 0030270 | molecular_function | formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0015948 | biological_process | methanogenesis |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| B | 0030270 | molecular_function | formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0015948 | biological_process | methanogenesis |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| C | 0030270 | molecular_function | formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0015948 | biological_process | methanogenesis |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
| D | 0019386 | biological_process | methanogenesis, from carbon dioxide |
| D | 0030270 | molecular_function | formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 701 |
| Chain | Residue |
| A | ASP57 |
| A | ILE190 |
| A | LYS191 |
| A | VAL193 |
| A | ALA196 |
| A | HOH6469 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K C 702 |
| Chain | Residue |
| C | PRO199 |
| D | GLU39 |
| C | THR41 |
| C | GLY44 |
| C | ALA54 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K D 703 |
| Chain | Residue |
| D | ASP57 |
| D | ILE190 |
| D | LYS191 |
| D | VAL193 |
| D | ALA196 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 704 |
| Chain | Residue |
| B | ASP57 |
| B | ILE190 |
| B | LYS191 |
| B | VAL193 |
| B | ALA196 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K C 705 |
| Chain | Residue |
| C | ASP57 |
| C | ILE190 |
| C | LYS191 |
| C | VAL193 |
| C | ALA196 |
| C | HOH6354 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 706 |
| Chain | Residue |
| A | GLU39 |
| B | THR41 |
| B | GLY44 |
| B | ALA54 |
| B | PRO199 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K D 707 |
| Chain | Residue |
| C | GLU39 |
| D | THR41 |
| D | GLY44 |
| D | ALA54 |
| D | PRO199 |
| D | HOH6108 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 708 |
| Chain | Residue |
| A | THR41 |
| A | GLY44 |
| A | ALA54 |
| A | PRO199 |
| B | GLU39 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 709 |
| Chain | Residue |
| B | VAL97 |
| B | MET98 |
| B | ALA100 |
| B | ALA103 |
| B | HOH6211 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K C 710 |
| Chain | Residue |
| C | VAL97 |
| C | MET98 |
| C | ALA100 |
| C | ALA103 |
| C | HOH6421 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 711 |
| Chain | Residue |
| A | VAL97 |
| A | MET98 |
| A | ALA100 |
| A | ALA103 |
| A | HOH6250 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K D 712 |
| Chain | Residue |
| D | VAL97 |
| D | MET98 |
| D | ALA100 |
| D | ALA103 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 713 |
| Chain | Residue |
| B | GLU113 |
| B | THR161 |
| B | THR162 |
| B | LEU251 |
| B | HOH6460 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K C 714 |
| Chain | Residue |
| C | GLU113 |
| C | THR161 |
| C | THR162 |
| C | LEU251 |
| C | HOH6206 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K D 715 |
| Chain | Residue |
| D | GLU113 |
| D | THR161 |
| D | THR162 |
| D | LEU251 |
| D | HOH6106 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K A 716 |
| Chain | Residue |
| A | GLU113 |
| A | THR161 |
| A | THR162 |
| A | LEU251 |
| A | HOH6252 |
| A | HOH6472 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE K B 717 |
| Chain | Residue |
| B | HIS293 |
| B | PHE296 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K D 718 |
| Chain | Residue |
| D | ARG22 |
| D | ASP107 |
| D | PHE158 |
| D | GLY159 |
| site_id | CC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MFN A 600 |
| Chain | Residue |
| B | LEU219 |
| B | ALA221 |
| B | HOH6474 |
| A | GLN95 |
| A | MET98 |
| A | LYS123 |
| A | PHE126 |
| A | PHE127 |
| B | SER46 |
| B | PHE200 |
| B | VAL205 |
| B | SER207 |
| B | SER209 |
| site_id | CC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE MFN C 601 |
| Chain | Residue |
| C | GLN95 |
| C | MET98 |
| C | TYR122 |
| C | LYS123 |
| C | PHE127 |
| D | ILE48 |
| D | MET49 |
| D | SER207 |
| D | SER209 |
| D | GLU245 |
| site_id | CC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE MFN B 602 |
| Chain | Residue |
| A | SER46 |
| A | MET49 |
| A | PHE200 |
| A | VAL205 |
| A | SER207 |
| A | SER209 |
| A | PHE218 |
| A | LEU219 |
| A | ALA221 |
| A | HOH6234 |
| B | GLN95 |
| B | MET98 |
| B | LYS123 |
| B | PHE126 |
| B | PHE127 |
