2FH1
C-terminal half of gelsolin soaked in low calcium at pH 4.5
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 2001 |
| Chain | Residue |
| A | GLY444 |
| A | ASP445 |
| A | GLU475 |
| A | THR524 |
| A | HOH2020 |
| A | HOH2079 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 2002 |
| Chain | Residue |
| A | HOH2044 |
| A | HOH2059 |
| A | ASN564 |
| A | ASP565 |
| A | GLU587 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 2003 |
| Chain | Residue |
| A | ASP669 |
| A | ASP670 |
| A | GLU692 |
| A | HOH2027 |
| A | HOH2030 |
| A | HOH2036 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 3001 |
| Chain | Residue |
| B | GLY444 |
| B | ASP445 |
| B | GLU475 |
| B | THR524 |
| B | HOH3063 |
| B | HOH3064 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 3002 |
| Chain | Residue |
| B | ASN564 |
| B | ASP565 |
| B | GLU587 |
| B | HOH3062 |
| B | HOH3068 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 3003 |
| Chain | Residue |
| B | ASP669 |
| B | ASP670 |
| B | GLU692 |
| B | HOH3034 |
| B | HOH3081 |
| B | HOH3146 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 4001 |
| Chain | Residue |
| C | GLY444 |
| C | ASP445 |
| C | GLU475 |
| C | THR524 |
| C | HOH4023 |
| C | HOH4133 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 4002 |
| Chain | Residue |
| C | ASN564 |
| C | ASP565 |
| C | GLU587 |
| C | HOH4008 |
| C | HOH4018 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 4003 |
| Chain | Residue |
| C | ASP669 |
| C | ASP670 |
| C | GLU692 |
| C | HOH4045 |
| C | HOH4061 |
| C | HOH4293 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 81 |
| Details | Repeat: {"description":"Gelsolin-like 4","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 198 |
| Details | Repeat: {"description":"Gelsolin-like 5","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12460571","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16466744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1H1V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 21 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12460571","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16466744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1H1V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FH1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FH2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12460571","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1H1V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12460571","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16466744","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1H1V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FH3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphotyrosine; by SRC","evidences":[{"source":"PubMed","id":"10210201","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P13020","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphotyrosine; by SRC; in vitro","evidences":[{"source":"PubMed","id":"10210201","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 150 |
| Details | Repeat: {"description":"Gelsolin-like 6","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
