Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 501 |
| Chain | Residue |
| A | ARG14 |
| A | GLY17 |
| A | PRO63 |
| A | HOH522 |
| A | HOH529 |
| B | HOH544 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 502 |
| Chain | Residue |
| A | GLN92 |
| A | HOH565 |
| A | GLY73 |
| A | THR74 |
| A | ASN88 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 503 |
| Chain | Residue |
| A | PRO1 |
| A | LYS55 |
| B | HIS69 |
| B | LYS70 |
| B | PHE99 |
| B | HOH563 |
| B | HOH577 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 504 |
| Chain | Residue |
| A | PRO39 |
| A | GLY40 |
| B | MET36 |
| B | ASN37 |
| B | HOH549 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 505 |
| Chain | Residue |
| B | LYS20 |
| B | GLU21 |
| B | ASN83 |
| B | HOH528 |
| B | HOH542 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE QNC A 504 |
| Chain | Residue |
| A | TRP6 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | GLY48 |
| A | ASN505 |
| A | HPH506 |
| A | HOH524 |
| B | ARG8 |
| B | PRO81 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ASN A 505 |
| Chain | Residue |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | GLY48 |
| A | QNC504 |
| A | HPH506 |
| A | HOH510 |
| A | HOH530 |
| B | ILE50 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HPH A 506 |
| Chain | Residue |
| A | ASP25 |
| A | GLY27 |
| A | GLY49 |
| A | ILE50 |
| A | QNC504 |
| A | ASN505 |
| A | DIQ507 |
| B | ASP25 |
| B | PRO81 |
| B | ILE84 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DIQ A 507 |
| Chain | Residue |
| A | ASP25 |
| A | PRO81 |
| A | ILE84 |
| A | HPH506 |
| A | NTB508 |
| A | HOH510 |
| B | ASP25 |
| B | GLY27 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NTB A 508 |
| Chain | Residue |
| A | DIQ507 |
| A | HOH518 |
| B | ALA28 |
| B | GLY48 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL |
| Chain | Residue | Details |
| A | ALA22-LEU33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| B | ASP25 | |
| B | THR26 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
