2FGH
ATP bound gelsolin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0005546 | molecular_function | phosphatidylinositol-4,5-bisphosphate binding |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0007417 | biological_process | central nervous system development |
| A | 0008154 | biological_process | actin polymerization or depolymerization |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0030030 | biological_process | cell projection organization |
| A | 0030031 | biological_process | cell projection assembly |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051014 | biological_process | actin filament severing |
| A | 0051015 | molecular_function | actin filament binding |
| A | 0051016 | biological_process | barbed-end actin filament capping |
| A | 0051693 | biological_process | actin filament capping |
| A | 0060271 | biological_process | cilium assembly |
| B | 0003779 | molecular_function | actin binding |
| B | 0005546 | molecular_function | phosphatidylinositol-4,5-bisphosphate binding |
| B | 0005615 | cellular_component | extracellular space |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0007417 | biological_process | central nervous system development |
| B | 0008154 | biological_process | actin polymerization or depolymerization |
| B | 0015629 | cellular_component | actin cytoskeleton |
| B | 0030030 | biological_process | cell projection organization |
| B | 0030031 | biological_process | cell projection assembly |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051014 | biological_process | actin filament severing |
| B | 0051015 | molecular_function | actin filament binding |
| B | 0051016 | biological_process | barbed-end actin filament capping |
| B | 0051693 | biological_process | actin filament capping |
| B | 0060271 | biological_process | cilium assembly |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ATP A 5380 |
| Chain | Residue |
| A | ARG363 |
| A | HIS638 |
| A | ASN368 |
| A | TRP369 |
| A | ARG370 |
| A | ASP371 |
| A | LYS503 |
| A | ARG542 |
| A | ARG629 |
| A | LEU630 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ATP B 9380 |
| Chain | Residue |
| B | ARG363 |
| B | ASN368 |
| B | TRP369 |
| B | ARG370 |
| B | ASP371 |
| B | LYS503 |
| B | ARG542 |
| B | ARG629 |
| B | LEU630 |
| B | HIS638 |
| B | HOH9400 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15215896, ECO:0007744|PDB:1RGI |
| Chain | Residue | Details |
| A | ASP66 | |
| A | ARG328 | |
| B | ASP66 | |
| B | ALA67 | |
| B | SER98 | |
| B | ASP110 | |
| B | ARG115 | |
| B | VAL117 | |
| B | ALA146 | |
| B | ASP303 | |
| B | CYS304 | |
| A | ALA67 | |
| B | ARG328 | |
| A | SER98 | |
| A | ASP110 | |
| A | ARG115 | |
| A | VAL117 | |
| A | ALA146 | |
| A | ASP303 | |
| A | CYS304 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER136 | |
| A | LEU162 | |
| B | SER136 | |
| B | LEU162 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P06396 |
| Chain | Residue | Details |
| A | ASP187 | |
| A | VAL495 | |
| A | SER525 | |
| A | ASP565 | |
| A | ALA566 | |
| A | LYS588 | |
| A | ASP670 | |
| A | VAL671 | |
| A | LYS693 | |
| B | ASP187 | |
| B | CYS188 | |
| A | CYS188 | |
| B | ARG210 | |
| B | THR260 | |
| B | ASP445 | |
| B | SER446 | |
| B | VAL476 | |
| B | GLU488 | |
| B | THR493 | |
| B | VAL495 | |
| B | SER525 | |
| B | ASP565 | |
| A | ARG210 | |
| B | ALA566 | |
| B | LYS588 | |
| B | ASP670 | |
| B | VAL671 | |
| B | LYS693 | |
| A | THR260 | |
| A | ASP445 | |
| A | SER446 | |
| A | VAL476 | |
| A | GLU488 | |
| A | THR493 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P06396 |
| Chain | Residue | Details |
| A | GLY60 | |
| B | ARG625 | |
| A | LEU383 | |
| A | GLY439 | |
| A | LEU577 | |
| A | ARG625 | |
| B | GLY60 | |
| B | LEU383 | |
| B | GLY439 | |
| B | LEU577 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P13020 |
| Chain | Residue | Details |
| A | ALA558 | |
| B | ALA558 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P06396 |
| Chain | Residue | Details |
| A | PRO716 | |
| B | PRO716 |
