2FEW
Complex of enzyme IIAMTL and phosphorylated enzyme IIBMTL from Escherichia coli NMR, restrained regularized mean structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0008982 | molecular_function | protein-N(PI)-phosphohistidine-sugar phosphotransferase activity |
| B | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
| B | 0022872 | molecular_function | protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 142 |
| Details | Domain: {"description":"PTS EIIA type-2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00417","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Tele-phosphohistidine intermediate; for EIIA activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00417","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12202490","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16443929","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9551558","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Stabilizes the transition state in the phosphoryl transfer from HPr to EIIA","evidences":[{"source":"PubMed","id":"9551558","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphohistidine; by HPr","evidences":[{"source":"PubMed","id":"3142516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12202490","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16443929","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"2407724","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9551558","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Phosphocysteine intermediate; for EIIB activity","evidences":[{"source":"PubMed","id":"15258141","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16443929","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphocysteine; by EIIA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00422","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"3142516","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15258141","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16443929","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"2407724","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
