Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0005575 | cellular_component | cellular_component |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0005575 | cellular_component | cellular_component |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM A 901 |
| Chain | Residue |
| A | TRP56 |
| A | HBI903 |
| A | HAR909 |
| A | NO1901 |
| A | HOH1911 |
| A | HOH1940 |
| A | HOH1986 |
| A | HOH2387 |
| A | SER59 |
| A | CYS62 |
| A | PHE231 |
| A | ASN232 |
| A | TRP234 |
| A | TRP325 |
| A | TYR351 |
| A | TYR353 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NO A 1901 |
| Chain | Residue |
| A | HEM901 |
| A | HAR909 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO B 2903 |
| Chain | Residue |
| A | HAR910 |
| B | PRO212 |
| B | ILE213 |
| B | ILE214 |
| B | PHE231 |
| B | NO1902 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NO B 1902 |
| Chain | Residue |
| A | HAR910 |
| B | PHE231 |
| B | HEM902 |
| B | NO2903 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HBI A 903 |
| Chain | Residue |
| A | ARG243 |
| A | THR324 |
| A | TRP325 |
| A | HEM901 |
| A | HOH2013 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE HBI B 904 |
| Chain | Residue |
| B | ARG243 |
| B | THR324 |
| B | TRP325 |
| B | PHE338 |
| B | HEM902 |
| site_id | AC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM B 902 |
| Chain | Residue |
| A | HAR910 |
| B | TRP56 |
| B | CYS62 |
| B | PHE231 |
| B | ASN232 |
| B | GLY233 |
| B | TRP234 |
| B | GLU239 |
| B | TRP325 |
| B | TYR351 |
| B | TYR353 |
| B | HBI904 |
| B | NO1902 |
| B | HOH2053 |
| B | HOH2303 |
| site_id | AC8 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HAR A 909 |
| Chain | Residue |
| A | GLN125 |
| A | ARG128 |
| A | TYR209 |
| A | GLY233 |
| A | TRP234 |
| A | TYR235 |
| A | GLU239 |
| A | ASN244 |
| A | HEM901 |
| A | NO1901 |
| A | HOH1986 |
| A | HOH2012 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HAR A 910 |
| Chain | Residue |
| B | GLN125 |
| B | ARG128 |
| B | TYR209 |
| B | GLY233 |
| B | TRP234 |
| B | TYR235 |
| B | GLU239 |
| B | ASN244 |
| B | HEM902 |
| B | NO1902 |
| B | NO2903 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCIGRLfW |
| Chain | Residue | Details |
| A | ARG61-TRP68 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue |
| Chain | Residue | Details |
| A | LEU89 | |
| B | LEU89 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| A | TRP234 | |
| A | CYS62 | |
| A | ARG65 | |
| A | GLU239 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| B | TRP234 | |
| B | CYS62 | |
| B | ARG65 | |
| B | GLU239 | |
