2FA3

HMG-CoA synthase from Brassica juncea in complex with acetyl-CoA and acetyl-cys117.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004421	molecular_function	hydroxymethylglutaryl-CoA synthase activity
A	0006084	biological_process	acetyl-CoA metabolic process
A	0006629	biological_process	lipid metabolic process
A	0006694	biological_process	steroid biosynthetic process
A	0008202	biological_process	steroid metabolic process
A	0008299	biological_process	isoprenoid biosynthetic process
A	0010142	biological_process	farnesyl diphosphate biosynthetic process, mevalonate pathway
A	0016126	biological_process	sterol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE ACO A 796

Chain	Residue
A	SER31
A	THR159
A	PHE192
A	VAL204
A	SER209
A	HIS247
A	PRO249
A	TYR250
A	LYS252
A	LYS256
A	ARG296
A	LYS32
A	ASN326
A	GLY33
A	LYS34
A	ILE37
A	GLY38
A	SCY117
A	TYR151
A	PRO155

---

Functional Information from PROSITE/UniProt

site_id	PS01226
Number of Residues	16
Details	HMG_COA_SYNTHASE Hydroxymethylglutaryl-coenzyme A synthase active site. NtDVEGVDstNACYgG

Chain	Residue	Details
A	ASN105-GLY120

---