2F9M
3D structure of active human Rab11b GTPase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001881 | biological_process | receptor recycling |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0003925 | molecular_function | G protein activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005768 | cellular_component | endosome |
| A | 0005794 | cellular_component | Golgi apparatus |
| A | 0005829 | cellular_component | cytosol |
| A | 0008021 | cellular_component | synaptic vesicle |
| A | 0015031 | biological_process | protein transport |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019003 | molecular_function | GDP binding |
| A | 0030670 | cellular_component | phagocytic vesicle membrane |
| A | 0030672 | cellular_component | synaptic vesicle membrane |
| A | 0031489 | molecular_function | myosin V binding |
| A | 0032402 | biological_process | melanosome transport |
| A | 0032456 | biological_process | endocytic recycling |
| A | 0033572 | biological_process | transferrin transport |
| A | 0035773 | biological_process | insulin secretion involved in cellular response to glucose stimulus |
| A | 0044070 | biological_process | regulation of monoatomic anion transport |
| A | 0045054 | biological_process | constitutive secretory pathway |
| A | 0045055 | biological_process | regulated exocytosis |
| A | 0045202 | cellular_component | synapse |
| A | 0045296 | molecular_function | cadherin binding |
| A | 0045335 | cellular_component | phagocytic vesicle |
| A | 0055037 | cellular_component | recycling endosome |
| A | 0055038 | cellular_component | recycling endosome membrane |
| A | 0070062 | cellular_component | extracellular exosome |
| A | 0071468 | biological_process | cellular response to acidic pH |
| A | 0090150 | biological_process | establishment of protein localization to membrane |
| A | 0150093 | biological_process | amyloid-beta clearance by transcytosis |
| A | 2000008 | biological_process | regulation of protein localization to cell surface |
| A | 2001135 | biological_process | regulation of endocytic recycling |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1201 |
| Chain | Residue |
| A | SER25 |
| A | THR43 |
| A | GNP1200 |
| A | HOH1211 |
| A | HOH1220 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 1202 |
| Chain | Residue |
| A | HOH1300 |
| A | HOH1348 |
| A | GLU108 |
| A | HIS112 |
| A | HOH1264 |
| A | HOH1281 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 1203 |
| Chain | Residue |
| A | MET7 |
| A | ASP183 |
| A | HIS187 |
| A | HOH1247 |
| A | HOH1483 |
| site_id | AC4 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE GNP A 1200 |
| Chain | Residue |
| A | SER20 |
| A | GLY21 |
| A | VAL22 |
| A | GLY23 |
| A | LYS24 |
| A | SER25 |
| A | ASN26 |
| A | PHE36 |
| A | ASN37 |
| A | LEU38 |
| A | SER40 |
| A | SER42 |
| A | THR43 |
| A | ALA68 |
| A | GLY69 |
| A | ASN124 |
| A | LYS125 |
| A | ASP127 |
| A | LEU128 |
| A | SER154 |
| A | ALA155 |
| A | LEU156 |
| A | MG1201 |
| A | HOH1211 |
| A | HOH1220 |
| A | HOH1221 |
| A | HOH1245 |
| A | HOH1282 |
| A | HOH1344 |
| A | HOH1464 |
Functional Information from PROSITE/UniProt
| site_id | PS00675 |
| Number of Residues | 14 |
| Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL |
| Chain | Residue | Details |
| A | VAL14-LEU27 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16545962 |
| Chain | Residue | Details |
| A | GLY18 | |
| A | ASP66 | |
| A | ASN124 | |
| A | SER154 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | GLN70 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | GLY21 |
