2F9L

3D structure of inactive human Rab11b GTPase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001881	biological_process	receptor recycling
A	0003924	molecular_function	GTPase activity
A	0003925	molecular_function	G protein activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005768	cellular_component	endosome
A	0005794	cellular_component	Golgi apparatus
A	0005829	cellular_component	cytosol
A	0008021	cellular_component	synaptic vesicle
A	0015031	biological_process	protein transport
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0019003	molecular_function	GDP binding
A	0030670	cellular_component	phagocytic vesicle membrane
A	0030672	cellular_component	synaptic vesicle membrane
A	0031489	molecular_function	myosin V binding
A	0032402	biological_process	melanosome transport
A	0032456	biological_process	endocytic recycling
A	0033572	biological_process	transferrin transport
A	0035773	biological_process	insulin secretion involved in cellular response to glucose stimulus
A	0044070	biological_process	regulation of monoatomic anion transport
A	0045054	biological_process	constitutive secretory pathway
A	0045055	biological_process	regulated exocytosis
A	0045202	cellular_component	synapse
A	0045296	molecular_function	cadherin binding
A	0045335	cellular_component	phagocytic vesicle
A	0055037	cellular_component	recycling endosome
A	0055038	cellular_component	recycling endosome membrane
A	0070062	cellular_component	extracellular exosome
A	0071468	biological_process	cellular response to acidic pH
A	0090150	biological_process	establishment of protein localization to membrane
A	0150093	biological_process	amyloid-beta clearance by transcytosis
A	2000008	biological_process	regulation of protein localization to cell surface
A	2001135	biological_process	regulation of endocytic recycling

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1175

Chain	Residue
A	SER25
A	GDP1174
A	HOH1296
A	HOH1297
A	HOH1298
A	HOH1299

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site_id	AC2
Number of Residues	25
Details	BINDING SITE FOR RESIDUE GDP A 1174

Chain	Residue
A	LYS24
A	SER25
A	ASN26
A	PHE36
A	ASN37
A	LEU38
A	ASN124
A	LYS125
A	ASP127
A	SER154
A	ALA155
A	LEU156
A	MG1175
A	HOH1190
A	HOH1201
A	HOH1216
A	HOH1222
A	HOH1240
A	HOH1241
A	HOH1296
A	HOH1298
A	HOH1299
A	GLY21
A	VAL22
A	GLY23

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Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL

Chain	Residue	Details
A	VAL14-LEU27

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16545962

Chain	Residue	Details
A	GLY18
A	ASP66
A	ASN124
A	SER154

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