2F9I

Crystal Structure of the carboxyltransferase subunit of ACC from Staphylococcus aureus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003824	molecular_function	catalytic activity
A	0003989	molecular_function	acetyl-CoA carboxylase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0009317	cellular_component	acetyl-CoA carboxylase complex
A	0016740	molecular_function	transferase activity
A	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
A	0016874	molecular_function	ligase activity
A	2001295	biological_process	malonyl-CoA biosynthetic process
B	0000166	molecular_function	nucleotide binding
B	0003989	molecular_function	acetyl-CoA carboxylase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0008270	molecular_function	zinc ion binding
B	0009317	cellular_component	acetyl-CoA carboxylase complex
B	0016740	molecular_function	transferase activity
B	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
B	0046872	molecular_function	metal ion binding
B	2001295	biological_process	malonyl-CoA biosynthetic process
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0003989	molecular_function	acetyl-CoA carboxylase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0009317	cellular_component	acetyl-CoA carboxylase complex
C	0016740	molecular_function	transferase activity
C	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
C	0016874	molecular_function	ligase activity
C	2001295	biological_process	malonyl-CoA biosynthetic process
D	0000166	molecular_function	nucleotide binding
D	0003989	molecular_function	acetyl-CoA carboxylase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006633	biological_process	fatty acid biosynthetic process
D	0008270	molecular_function	zinc ion binding
D	0009317	cellular_component	acetyl-CoA carboxylase complex
D	0016740	molecular_function	transferase activity
D	0016743	molecular_function	carboxyl- or carbamoyltransferase activity
D	0046872	molecular_function	metal ion binding
D	2001295	biological_process	malonyl-CoA biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 601

Chain	Residue
B	CYS33
B	CYS36
B	CYS52
B	CYS55

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 602

Chain	Residue
D	CYS33
D	CYS36
D	CYS52
D	CYS55

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	257
Details	Domain: {"description":"CoA carboxyltransferase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01137","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	256
Details	Domain: {"description":"CoA carboxyltransferase N-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01136","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	44
Details	Zinc finger: {"description":"C4-type","evidences":[{"source":"HAMAP-Rule","id":"MF_01395","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01395","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
A	GLY199
A	GLY200
B	GLY207
B	GLY208

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
D	GLY207
D	GLY208
C	GLY199
C	GLY200

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
A	SER198
A	GLY197

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1xny

Chain	Residue	Details
C	SER198
C	GLY197

---