2F8T
Crystal structure of Aa-Ago with externally-bound siRNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q746M7 |
| Chain | Residue | Details |
| A | ASP502 | |
| A | GLU541 | |
| A | ASP571 | |
| A | ASP683 | |
| B | ASP502 | |
| B | GLU541 | |
| B | ASP571 | |
| B | ASP683 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q746M7, ECO:0000305|PubMed:16061186, ECO:0007744|PDB:1YVU |
| Chain | Residue | Details |
| A | ASP502 | |
| A | ASP683 | |
| B | ASP502 | |
| B | ASP683 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q746M7 |
| Chain | Residue | Details |
| A | ASP571 | |
| B | ASP571 |
