Functional Information from GO Data
Chain | GOid | namespace | contents |
E | 0004175 | molecular_function | endopeptidase activity |
E | 0004252 | molecular_function | serine-type endopeptidase activity |
E | 0005515 | molecular_function | protein binding |
E | 0005576 | cellular_component | extracellular region |
E | 0005615 | cellular_component | extracellular space |
E | 0006508 | biological_process | proteolysis |
E | 0007586 | biological_process | digestion |
E | 0008236 | molecular_function | serine-type peptidase activity |
E | 0046872 | molecular_function | metal ion binding |
E | 0097180 | cellular_component | serine protease inhibitor complex |
E | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 E 239 |
Chain | Residue |
E | TYR20 |
E | THR21 |
E | SER107 |
E | ALA108 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 E 240 |
Chain | Residue |
E | VAL17 |
E | LYS140 |
E | SER141 |
E | SER142 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 I 103 |
Chain | Residue |
I | TYR23 |
I | SER24 |
I | THR28 |
I | HOH112 |
E | THR144 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 E 241 |
Chain | Residue |
E | ASN92 |
E | THR95 |
E | ASN97 |
E | ASN98 |
E | LYS154 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA E 242 |
Chain | Residue |
E | GLU67 |
E | ASN69 |
E | VAL72 |
E | GLU74 |
E | GLU77 |
E | HOH261 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
Chain | Residue | Details |
E | VAL51-CYS56 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
Chain | Residue | Details |
E | ASP186-VAL197 | |
site_id | PS00282 |
Number of Residues | 24 |
Details | KAZAL_1 Kazal serine protease inhibitors family signature. CprvlHrvCgSdgntYsnpCtldC |
Chain | Residue | Details |
I | CYS8-CYS31 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
E | LYS58 | |
E | LEU102 | |
E | PRO195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 7 |
Details | BINDING: |
Chain | Residue | Details |
E | ILE70 | |
E | VAL72 | |
E | GLY75 | |
E | ILE80 | |
E | GLN189 | |
E | SER192 | |
E | PRO195 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | ASP99 | |
E | HIS55 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | SER192 | |
E | GLY193 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | SER192 | |
E | GLY190 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | SER192 | |
E | ASP99 | |
E | HIS55 | |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | SER192 | |
E | ASP99 | |
E | HIS55 | |
E | GLY190 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
E | SER192 | |
E | GLY193 | |
E | ASP99 | |
E | HIS55 | |