2F33

NMR solution structure of Ca2+-loaded calbindin D28K

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005499	molecular_function	vitamin D binding
A	0005509	molecular_function	calcium ion binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0007611	biological_process	learning or memory
A	0007614	biological_process	short-term memory
A	0007616	biological_process	long-term memory
A	0007626	biological_process	locomotory behavior
A	0008270	molecular_function	zinc ion binding
A	0010842	biological_process	retina layer formation
A	0010996	biological_process	response to auditory stimulus
A	0030424	cellular_component	axon
A	0030425	cellular_component	dendrite
A	0032420	cellular_component	stereocilium
A	0032437	cellular_component	cuticular plate
A	0035502	biological_process	metanephric part of ureteric bud development
A	0042359	biological_process	vitamin D metabolic process
A	0043005	cellular_component	neuron projection
A	0043025	cellular_component	neuronal cell body
A	0043195	cellular_component	terminal bouton
A	0044305	cellular_component	calyx of Held
A	0045202	cellular_component	synapse
A	0046872	molecular_function	metal ion binding
A	0048167	biological_process	regulation of synaptic plasticity
A	0055074	biological_process	calcium ion homeostasis
A	0060041	biological_process	retina development in camera-type eye
A	0072205	biological_process	metanephric collecting duct development
A	0072221	biological_process	metanephric distal convoluted tubule development
A	0072286	biological_process	metanephric connecting tubule development
A	0090102	biological_process	cochlea development
A	0098686	cellular_component	hippocampal mossy fiber to CA3 synapse
A	0098794	cellular_component	postsynapse
A	0098978	cellular_component	glutamatergic synapse
A	0098982	cellular_component	GABA-ergic synapse
A	0099509	biological_process	regulation of presynaptic cytosolic calcium ion concentration
A	0099523	cellular_component	presynaptic cytosol
A	0099524	cellular_component	postsynaptic cytosol
A	0099534	molecular_function	calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration
A	0099566	biological_process	regulation of postsynaptic cytosolic calcium ion concentration
A	0099567	molecular_function	calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DADGSGYLEgkEL

Chain	Residue	Details
A	ASP24-LEU36
A	ASP111-LEU123
A	ASP155-MET167
A	ASP199-LEU211

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	35
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	35
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	35
Details	Domain: {"description":"EF-hand 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Region: {"description":"Interaction with RANBP9","evidences":[{"source":"UniProtKB","id":"P05937","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	19
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"1988053","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---