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2F33

NMR solution structure of Ca2+-loaded calbindin D28K

Functional Information from GO Data
ChainGOidnamespacecontents
A0005499molecular_functionvitamin D binding
A0005509molecular_functioncalcium ion binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0007611biological_processlearning or memory
A0007614biological_processshort-term memory
A0007616biological_processlong-term memory
A0007626biological_processlocomotory behavior
A0008270molecular_functionzinc ion binding
A0010842biological_processretina layer formation
A0010996biological_processresponse to auditory stimulus
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0032420cellular_componentstereocilium
A0032437cellular_componentcuticular plate
A0035502biological_processmetanephric part of ureteric bud development
A0042359biological_processvitamin D metabolic process
A0043005cellular_componentneuron projection
A0043025cellular_componentneuronal cell body
A0043195cellular_componentterminal bouton
A0043197cellular_componentdendritic spine
A0044305cellular_componentcalyx of Held
A0045202cellular_componentsynapse
A0046872molecular_functionmetal ion binding
A0048167biological_processregulation of synaptic plasticity
A0055074biological_processcalcium ion homeostasis
A0060041biological_processretina development in camera-type eye
A0072205biological_processmetanephric collecting duct development
A0072221biological_processmetanephric distal convoluted tubule development
A0072286biological_processmetanephric connecting tubule development
A0090102biological_processcochlea development
A0098686cellular_componenthippocampal mossy fiber to CA3 synapse
A0098794cellular_componentpostsynapse
A0098978cellular_componentglutamatergic synapse
A0098982cellular_componentGABA-ergic synapse
A0099509biological_processregulation of presynaptic cytosolic calcium ion concentration
A0099523cellular_componentpresynaptic cytosol
A0099524cellular_componentpostsynaptic cytosol
A0099534molecular_functioncalcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration
A0099566biological_processregulation of postsynaptic cytosolic calcium ion concentration
A0099567molecular_functioncalcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration
A1900271biological_processregulation of long-term synaptic potentiation
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DADGSGYLEgkEL
ChainResidueDetails
AASP24-LEU36
AASP111-LEU123
AASP155-MET167
AASP199-LEU211

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues19
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00448
ChainResidueDetails
AASP24
AASP155
AASN157
AASP159
ALYS161
AGLU166
AASP199
AASP201
AASN203
ATYR205
AGLU210
AASP26
ASER28
ATYR30
AGLU35
AASP111
AASP113
ASER115
AGLU122

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000269|PubMed:1988053
ChainResidueDetails
AALA2

226707

PDB entries from 2024-10-30

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