2EZE
SOLUTION STRUCTURE OF A COMPLEX OF THE SECOND DNA BINDING DOMAIN OF HUMAN HMG-I(Y) BOUND TO DNA DODECAMER CONTAINING THE PRDII SITE OF THE INTERFERON-BETA PROMOTER, NMR, 35 STRUCTURES
Functional Information from GO Data
Functional Information from PROSITE/UniProt
| site_id | PS00354 |
| Number of Residues | 11 |
| Details | HMGI_Y HMG-I and HMG-Y DNA-binding domain (A+T-hook). Tp.KRPRGRPKg |
| Chain | Residue | Details |
| A | THR5-GLY15 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | DNA_BIND: A.T hook 2 |
| Chain | Residue | Details |
| A | LYS17-THR27 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | VAL3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | ARG8 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | PRO13 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by HIPK2 and CDC2 => ECO:0007744|PubMed:17924679, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | LYS17 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Omega-N-methylarginine; by PRMT6; alternate => ECO:0000269|PubMed:16159886 |
| Chain | Residue | Details |
| A | ALA22 | |
| A | THR24 |
