2EXF

Solution structure of the HIV-1 nucleocapsid (NCp7(12-55)) complexed with the DNA (-) Primer Binding Site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 56

Chain	Residue
A	CYS15
A	CYS18
A	HIS23
A	CYS28

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 57

Chain	Residue
A	CYS36
A	CYS39
A	HIS44
A	CYS49

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	17
Details	ZN_FING: CCHC-type 1 => ECO:0000255|PROSITE-ProRule:PRU00047

Chain	Residue	Details
A	LYS14-PRO31

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site_id	SWS_FT_FI2
Number of Residues	17
Details	ZN_FING: CCHC-type 2 => ECO:0000255|PROSITE-ProRule:PRU00047

Chain	Residue	Details
A	GLY35-ARG52

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Cleavage; by viral protease => ECO:0000255

Chain	Residue	Details
A	ASN55

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Asymmetric dimethylarginine; in Nucleocapsid protein p7; by host PRMT6 => ECO:0000269|PubMed:17415034

Chain	Residue	Details
A	LYS33

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