2EX2

Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000270	biological_process	peptidoglycan metabolic process
A	0004175	molecular_function	endopeptidase activity
A	0004180	molecular_function	carboxypeptidase activity
A	0004185	molecular_function	serine-type carboxypeptidase activity
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008360	biological_process	regulation of cell shape
A	0008658	molecular_function	penicillin binding
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0042597	cellular_component	periplasmic space
A	0043093	biological_process	FtsZ-dependent cytokinesis
A	0046677	biological_process	response to antibiotic
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 501

Chain	Residue
A	LEU392
A	LYS413
A	SER415
A	PHE430
A	THR432
A	ARG438
A	HOH1308

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Acyl-ester intermediate => ECO:0000250|UniProtKB:P39844

Chain	Residue	Details
A	SER62

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P39844

Chain	Residue	Details
A	LYS65

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site_id	SWS_FT_FI3
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P39844

Chain	Residue	Details
A	SER306

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	LYS417

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