2EWM
Crystal Structure of the (S)-Specific 1-Phenylethanol Dehydrogenase of the Denitrifying Bacterium Strain EbN1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0010130 | biological_process | anaerobic ethylbenzene catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0051289 | biological_process | protein homotetramerization |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0010130 | biological_process | anaerobic ethylbenzene catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0051289 | biological_process | protein homotetramerization |
| B | 0055114 | biological_process | obsolete oxidation-reduction process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 701 |
| Chain | Residue |
| A | HIS249 |
| A | HIS249 |
| B | TYR144 |
| B | TYR144 |
| B | TRP145 |
| B | TRP145 |
| B | ARG166 |
| B | ARG166 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 702 |
| Chain | Residue |
| A | TYR144 |
| A | TRP145 |
| A | TRP145 |
| A | ARG166 |
| A | ARG166 |
| B | HIS249 |
| B | HIS249 |
| A | TYR144 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAD B 256 |
| Chain | Residue |
| B | GLY14 |
| B | ASN17 |
| B | GLY18 |
| B | ILE19 |
| B | ASP38 |
| B | LEU39 |
| B | CYS61 |
| B | ASP62 |
| B | VAL63 |
| B | ASN89 |
| B | ALA90 |
| B | TYR93 |
| B | ILE112 |
| B | THR140 |
| B | SER141 |
| B | TYR154 |
| B | LYS158 |
| B | PRO184 |
| B | SER185 |
| B | LEU186 |
| B | VAL187 |
| B | THR189 |
| B | THR191 |
| B | THR192 |
| B | HOH742 |
| B | HOH786 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAD A 257 |
| Chain | Residue |
| A | GLY14 |
| A | ASN17 |
| A | GLY18 |
| A | ILE19 |
| A | ASP38 |
| A | LEU39 |
| A | CYS61 |
| A | ASP62 |
| A | VAL63 |
| A | ASN89 |
| A | TYR93 |
| A | THR140 |
| A | SER141 |
| A | TYR154 |
| A | LYS158 |
| A | PRO184 |
| A | SER185 |
| A | LEU186 |
| A | VAL187 |
| A | THR189 |
| A | THR191 |
| A | THR192 |
| A | HOH760 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | TYR154 | |
| B | TYR154 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16388583 |
| Chain | Residue | Details |
| A | CYS61 | |
| A | ASN89 | |
| A | TYR93 | |
| A | LYS158 | |
| A | PRO184 | |
| A | THR191 | |
| B | ASN17 | |
| B | ASP38 | |
| B | CYS61 | |
| B | ASN89 | |
| B | TYR93 | |
| B | LYS158 | |
| B | PRO184 | |
| B | THR191 | |
| A | ASN17 | |
| A | ASP38 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER141 | |
| B | SER141 |
