Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 500 |
| Chain | Residue |
| A | HIS229 |
| A | HIS233 |
| A | GLU267 |
| A | HOH574 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | HOH579 |
| A | ARG27 |
| A | ARG122 |
| A | ILE132 |
| A | ALA133 |
| A | ILE176 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 501 |
| Chain | Residue |
| B | HIS229 |
| B | HIS233 |
| B | GLU267 |
| B | HOH572 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 503 |
| Chain | Residue |
| B | THR130 |
| B | THR136 |
| B | GLY152 |
| B | ASP311 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 504 |
| Chain | Residue |
| B | ARG27 |
| B | ARG122 |
| B | ILE132 |
| B | ALA133 |
| B | ILE176 |
| B | HOH549 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 505 |
| Chain | Residue |
| B | LYS37 |
| B | ASP40 |
| B | ARG41 |
| B | HOH603 |
| B | HOH679 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. ILMHELIHVL |
| Chain | Residue | Details |
| A | ILE226-LEU235 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LEU231 | |
| B | LEU231 | |
| Chain | Residue | Details |
| A | GLU230 | |
| A | VAL234 | |
| B | GLU230 | |
| B | VAL234 | |
| Chain | Residue | Details |
| A | LEU268 | |
| B | LEU268 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1i1e |
| Chain | Residue | Details |
| A | TYR372 | |
| A | ARG369 | |
| A | GLU267 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1i1e |
| Chain | Residue | Details |
| B | TYR372 | |
| B | ARG369 | |
| B | GLU267 | |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 626 |
| Chain | Residue | Details |
| A | GLU230 | metal ligand |
| A | LEU231 | proton acceptor, proton donor |
| A | VAL234 | metal ligand |
| A | LEU268 | metal ligand |
| A | ALA370 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 626 |
| Chain | Residue | Details |
| B | GLU230 | metal ligand |
| B | LEU231 | proton acceptor, proton donor |
| B | VAL234 | metal ligand |
| B | LEU268 | metal ligand |
| B | ALA370 | electrostatic stabiliser |
