2ERO
Crystal structure of vascular apoptosis-inducing protein-1(orthorhombic crystal form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00276, ECO:0000305 |
| Chain | Residue | Details |
| A | GLU336 | |
| B | GLU336 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00276, ECO:0000269|PubMed:16688218, ECO:0007744|PDB:2ERO, ECO:0007744|PDB:2ERP, ECO:0007744|PDB:2ERQ |
| Chain | Residue | Details |
| A | HIS335 | |
| A | HIS339 | |
| A | HIS345 | |
| B | HIS335 | |
| B | HIS339 | |
| B | HIS345 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16688218, ECO:0007744|PDB:2ERO, ECO:0007744|PDB:2ERP, ECO:0007744|PDB:2ERQ |
| Chain | Residue | Details |
| A | PHE410 | |
| A | GLU412 | |
| A | GLU415 | |
| A | ASP418 | |
| A | ASP469 | |
| A | MET470 | |
| A | ASP472 | |
| A | ASP483 | |
| A | ARG484 | |
| B | VAL405 | |
| B | ASN408 | |
| B | PHE410 | |
| B | GLU412 | |
| B | GLU415 | |
| B | ASP418 | |
| B | ASP469 | |
| B | MET470 | |
| B | ASP472 | |
| B | ASP483 | |
| B | ARG484 | |
| A | VAL405 | |
| A | ASN408 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Pyrrolidone carboxylic acid (Glu) => ECO:0000250|UniProtKB:P0DM89 |
| Chain | Residue | Details |
| A | GLU190 | |
| B | GLU190 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16688218, ECO:0007744|PDB:2ERO, ECO:0007744|PDB:2ERP, ECO:0007744|PDB:2ERQ |
| Chain | Residue | Details |
| A | ASN218 | |
| B | ASN218 |
