2EQ7
Crystal structure of lipoamide dehydrogenase from thermus thermophilus HB8 with psbdo
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004148 | molecular_function | dihydrolipoyl dehydrogenase (NADH) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006103 | biological_process | 2-oxoglutarate metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004148 | molecular_function | dihydrolipoyl dehydrogenase (NADH) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006103 | biological_process | 2-oxoglutarate metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016668 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0016746 | molecular_function | acyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD A 2482 |
| Chain | Residue |
| A | GLY8 |
| A | CYS40 |
| A | ARG42 |
| A | GLY44 |
| A | CYS45 |
| A | LYS49 |
| A | GLY109 |
| A | THR110 |
| A | ALA111 |
| A | ALA136 |
| A | THR137 |
| A | GLY10 |
| A | GLY138 |
| A | SER139 |
| A | SER157 |
| A | ILE178 |
| A | ARG262 |
| A | TYR265 |
| A | GLY301 |
| A | ASP302 |
| A | MET308 |
| A | LEU309 |
| A | PRO11 |
| A | ALA310 |
| A | HIS311 |
| A | ALA313 |
| A | TYR341 |
| A | HOH2484 |
| A | HOH2486 |
| A | HOH2489 |
| A | HOH2648 |
| B | HIS434 |
| A | GLY12 |
| A | GLU31 |
| A | LYS32 |
| A | GLU33 |
| A | GLY38 |
| A | THR39 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAD A 2483 |
| Chain | Residue |
| A | TRP146 |
| A | GLY174 |
| A | GLY176 |
| A | ILE178 |
| A | GLU181 |
| A | LEU196 |
| A | GLU197 |
| A | TYR198 |
| A | MET199 |
| A | GLY261 |
| A | ARG262 |
| A | MET308 |
| A | LEU309 |
| A | HOH2493 |
| A | HOH2505 |
| A | HOH2529 |
| A | HOH2532 |
| A | HOH2713 |
| A | HOH2754 |
| A | HOH2795 |
| A | HOH2800 |
| A | HOH2977 |
| site_id | AC3 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD B 1482 |
| Chain | Residue |
| A | HIS434 |
| B | GLY8 |
| B | GLY10 |
| B | PRO11 |
| B | GLY12 |
| B | GLU31 |
| B | LYS32 |
| B | GLU33 |
| B | GLY38 |
| B | THR39 |
| B | CYS40 |
| B | ARG42 |
| B | GLY44 |
| B | CYS45 |
| B | LYS49 |
| B | GLY109 |
| B | THR110 |
| B | ALA111 |
| B | ALA136 |
| B | THR137 |
| B | GLY138 |
| B | SER139 |
| B | ILE178 |
| B | ARG262 |
| B | TYR265 |
| B | GLY301 |
| B | ASP302 |
| B | MET308 |
| B | LEU309 |
| B | ALA310 |
| B | HIS311 |
| B | TYR341 |
| B | HOH1484 |
| B | HOH1490 |
| B | HOH1491 |
| B | HOH1494 |
| B | HOH1741 |
| site_id | AC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAD B 1483 |
| Chain | Residue |
| B | GLY176 |
| B | ILE178 |
| B | GLU181 |
| B | LEU196 |
| B | GLU197 |
| B | TYR198 |
| B | MET199 |
| B | ALA259 |
| B | GLY261 |
| B | MET308 |
| B | LEU309 |
| B | HOH1501 |
| B | HOH1509 |
| B | HOH1524 |
| B | HOH1536 |
| B | HOH1621 |
| B | HOH1668 |
| B | HOH1698 |
| B | HOH1743 |
| B | HOH1763 |
| B | HOH1972 |
| B | TRP146 |
| B | GLY174 |
Functional Information from PROSITE/UniProt
| site_id | PS00076 |
| Number of Residues | 11 |
| Details | PYRIDINE_REDOX_1 Pyridine nucleotide-disulphide oxidoreductases class-I active site. GGtCLrvGCIP |
| Chain | Residue | Details |
| A | GLY37-PRO47 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1get |
| Chain | Residue | Details |
| A | GLU439 | |
| A | HIS434 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1get |
| Chain | Residue | Details |
| B | GLU439 | |
| B | HIS434 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1get |
| Chain | Residue | Details |
| A | CYS40 | |
| A | CYS45 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1get |
| Chain | Residue | Details |
| B | CYS40 | |
| B | CYS45 |
