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2ENI

Mutant F197M structure of PH0725 from Pyrococcus horikoshii OT3

Functional Information from GO Data
ChainGOidnamespacecontents
A0004164molecular_functiondiphthine synthase activity
A0008168molecular_functionmethyltransferase activity
A0017183biological_processprotein histidyl modification to diphthamide
A0032259biological_processmethylation
B0004164molecular_functiondiphthine synthase activity
B0008168molecular_functionmethyltransferase activity
B0017183biological_processprotein histidyl modification to diphthamide
B0032259biological_processmethylation
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 302
ChainResidue
ATYR117
AHOH348
BGLY131
BHOH352
BHOH353
BHOH354

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE SAH A 301
ChainResidue
AGLY86
AASP87
AVAL90
AALA91
ASER115
AILE116
APHE165
ALEU166
ALEU206
AARG208
AALA209
APRO233
AHIS234
AILE235
AHOH397
ALEU10
ATHR36
ASER37

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01084, ECO:0000305|PubMed:18391406, ECO:0000305|Ref.4
ChainResidueDetails
ALEU10
AHIS234
BLEU10
BASP87
BVAL90
BSER115
BLEU166
BALA209
BHIS234
AASP87
AVAL90
ASER115
ALEU166
AALA209

219869

PDB entries from 2024-05-15

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