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2ELI

Solution structure of the second Phorbol esters/diacylglycerol binding domain of human Protein kinase C alpha type

Functional Information from GO Data
ChainGOidnamespacecontents
A0004674molecular_functionprotein serine/threonine kinase activity
A0005524molecular_functionATP binding
A0006468biological_processprotein phosphorylation
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ZN A 201
ChainResidue
AHIS18
ALYS19
APHE20
ACYS48
ACYS51

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE ZN A 401
ChainResidue
ACYS31
ACYS34
AHIS56

Functional Information from PROSITE/UniProt
site_idPS00479
Number of Residues50
DetailsZF_DAG_PE_1 Zinc finger phorbol-ester/DAG-type signature. HkFkihtygsptf.CdhCgslLyglihqgmk.CdtCdmnvHkqCvinvpsl..C
ChainResidueDetails
AHIS18-CYS67

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues50
DetailsZN_FING: Phorbol-ester/DAG-type 2 => ECO:0000255|PROSITE-ProRule:PRU00226
ChainResidueDetails
ALYS17-CYS67

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PDB entries from 2024-10-30

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