2EL9
Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004821 | molecular_function | histidine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0004821 | molecular_function | histidine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| B | 0042803 | molecular_function | protein homodimerization activity |
| C | 0004821 | molecular_function | histidine-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| C | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| C | 0042803 | molecular_function | protein homodimerization activity |
| D | 0004821 | molecular_function | histidine-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| D | 0006427 | biological_process | histidyl-tRNA aminoacylation |
| D | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HSS A 510 |
| Chain | Residue |
| A | GLU83 |
| A | GLU131 |
| A | ARG259 |
| A | TYR263 |
| A | TYR264 |
| A | THR281 |
| A | ALA284 |
| A | TYR288 |
| A | GLY304 |
| A | PHE305 |
| A | ALA306 |
| A | THR85 |
| A | GLY308 |
| A | ARG311 |
| A | ARG113 |
| A | GLU115 |
| A | GLY120 |
| A | ARG121 |
| A | TYR122 |
| A | PHE125 |
| A | GLN127 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HSS B 610 |
| Chain | Residue |
| B | GLU83 |
| B | THR85 |
| B | ARG113 |
| B | GLU115 |
| B | GLY120 |
| B | ARG121 |
| B | TYR122 |
| B | PHE125 |
| B | GLN127 |
| B | GLU131 |
| B | ARG259 |
| B | TYR263 |
| B | TYR264 |
| B | THR281 |
| B | TYR288 |
| B | GLY304 |
| B | PHE305 |
| B | ALA306 |
| B | GLY308 |
| B | ARG311 |
| B | HOH611 |
| B | HOH620 |
| site_id | AC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE HSS C 710 |
| Chain | Residue |
| C | GLU83 |
| C | THR85 |
| C | ARG113 |
| C | GLU115 |
| C | GLY120 |
| C | ARG121 |
| C | TYR122 |
| C | PHE125 |
| C | GLN127 |
| C | GLU131 |
| C | ARG259 |
| C | TYR263 |
| C | TYR264 |
| C | THR281 |
| C | ALA284 |
| C | GLY285 |
| C | TYR288 |
| C | GLY304 |
| C | PHE305 |
| C | ALA306 |
| C | GLY308 |
| C | ARG311 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HSS D 810 |
| Chain | Residue |
| D | GLU83 |
| D | THR85 |
| D | ARG113 |
| D | GLU115 |
| D | GLY120 |
| D | ARG121 |
| D | TYR122 |
| D | PHE125 |
| D | GLN127 |
| D | GLU131 |
| D | ARG259 |
| D | LEU261 |
| D | TYR263 |
| D | TYR264 |
| D | THR281 |
| D | ALA284 |
| D | TYR288 |
| D | GLY304 |
| D | PHE305 |
| D | ALA306 |
| D | GLY308 |
| D | ARG311 |
| D | HOH811 |
| D | HOH820 |
| D | HOH844 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qf6 |
| Chain | Residue | Details |
| A | ARG113 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qf6 |
| Chain | Residue | Details |
| B | ARG113 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qf6 |
| Chain | Residue | Details |
| C | ARG113 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1qf6 |
| Chain | Residue | Details |
| D | ARG113 |
