2EHJ
Structure of Uracil phosphoribosyl transferase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006206 | biological_process | pyrimidine nucleobase metabolic process |
| A | 0006223 | biological_process | uracil salvage |
| A | 0016020 | cellular_component | membrane |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0044206 | biological_process | UMP salvage |
| A | 0097216 | molecular_function | guanosine tetraphosphate binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006206 | biological_process | pyrimidine nucleobase metabolic process |
| B | 0006223 | biological_process | uracil salvage |
| B | 0016020 | cellular_component | membrane |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0044206 | biological_process | UMP salvage |
| B | 0097216 | molecular_function | guanosine tetraphosphate binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006206 | biological_process | pyrimidine nucleobase metabolic process |
| C | 0006223 | biological_process | uracil salvage |
| C | 0016020 | cellular_component | membrane |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0044206 | biological_process | UMP salvage |
| C | 0097216 | molecular_function | guanosine tetraphosphate binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004845 | molecular_function | uracil phosphoribosyltransferase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006206 | biological_process | pyrimidine nucleobase metabolic process |
| D | 0006223 | biological_process | uracil salvage |
| D | 0016020 | cellular_component | membrane |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0044206 | biological_process | UMP salvage |
| D | 0097216 | molecular_function | guanosine tetraphosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 209 |
| Chain | Residue |
| A | LYS1 |
| A | LYS2 |
| A | LEU169 |
| A | GLU170 |
| A | HIS173 |
| A | PRO174 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 209 |
| Chain | Residue |
| B | GLU170 |
| B | HIS173 |
| B | PRO174 |
| B | LYS1 |
| B | LYS2 |
| B | LEU169 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 209 |
| Chain | Residue |
| C | LYS1 |
| C | LYS2 |
| C | ILE166 |
| C | LEU169 |
| C | GLU170 |
| C | HIS173 |
| C | PRO174 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 209 |
| Chain | Residue |
| D | LYS1 |
| D | LYS2 |
| D | LEU169 |
| D | GLU170 |
| D | HIS173 |
| D | PRO174 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 210 |
| Chain | Residue |
| A | ARG103 |
| A | ALA134 |
| A | THR135 |
| A | GLY136 |
| A | GLY137 |
| A | SER138 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 210 |
| Chain | Residue |
| B | ARG103 |
| B | ALA134 |
| B | THR135 |
| B | GLY136 |
| B | GLY137 |
| B | SER138 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 210 |
| Chain | Residue |
| C | ALA134 |
| C | THR135 |
| C | GLY136 |
| C | GLY137 |
| C | SER138 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 210 |
| Chain | Residue |
| D | ARG103 |
| D | ALA134 |
| D | THR135 |
| D | GLY136 |
| D | GLY137 |
| D | SER138 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 211 |
| Chain | Residue |
| A | LYS69 |
| A | LYS70 |
| A | ARG95 |
| A | ARG124 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 211 |
| Chain | Residue |
| C | LYS69 |
| C | LYS70 |
| C | ARG95 |
| C | ARG124 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 211 |
| Chain | Residue |
| D | LYS69 |
| D | LYS70 |
| D | ARG95 |
| D | ARG124 |
| D | HOH226 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 212 |
| Chain | Residue |
| A | ARG78 |
| A | ALA79 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 211 |
| Chain | Residue |
| B | ARG78 |
| B | ALA79 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 212 |
| Chain | Residue |
| C | LEU77 |
| C | ARG78 |
| C | ALA79 |
| C | ARG103 |
| C | GLY201 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 212 |
| Chain | Residue |
| D | LEU77 |
| D | ARG78 |
| D | ALA79 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 213 |
| Chain | Residue |
| C | SER24 |
| C | THR25 |
| D | LYS70 |
| D | ARG95 |
| D | HOH220 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 213 |
| Chain | Residue |
| C | ARG95 |
| D | SER24 |
| D | THR25 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 213 |
| Chain | Residue |
| A | ARG95 |
| B | SER24 |
| B | THR25 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 212 |
| Chain | Residue |
| A | SER24 |
| A | THR25 |
| B | LYS70 |
| B | ARG95 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd3 |
| Chain | Residue | Details |
| A | ASP199 | |
| A | ARG103 | |
| A | THR107 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd3 |
| Chain | Residue | Details |
| B | ASP199 | |
| B | ARG103 | |
| B | THR107 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd3 |
| Chain | Residue | Details |
| C | ASP199 | |
| C | ARG103 | |
| C | THR107 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1bd3 |
| Chain | Residue | Details |
| D | ASP199 | |
| D | ARG103 | |
| D | THR107 |
