2EFY
Crystal Structure of T.th. HB8 O-acetylserine sulfhydrylase Complexed with 4-Acetylbutyric acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004124 | molecular_function | cysteine synthase activity |
| A | 0006535 | biological_process | cysteine biosynthetic process from serine |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0019344 | biological_process | cysteine biosynthetic process |
| B | 0004124 | molecular_function | cysteine synthase activity |
| B | 0006535 | biological_process | cysteine biosynthetic process from serine |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PLP A 413 |
| Chain | Residue |
| A | LYS40 |
| A | GLY219 |
| A | SER263 |
| A | PRO289 |
| A | ASP290 |
| A | HOH417 |
| A | HOH430 |
| A | ASN72 |
| A | TYR172 |
| A | GLY173 |
| A | GLY175 |
| A | THR176 |
| A | GLY177 |
| A | THR179 |
| A | GLN218 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP B 913 |
| Chain | Residue |
| B | LYS40 |
| B | ASN72 |
| B | TYR172 |
| B | GLY173 |
| B | GLY175 |
| B | THR176 |
| B | GLY177 |
| B | THR179 |
| B | GLN218 |
| B | GLY219 |
| B | SER263 |
| B | PRO289 |
| B | ASP290 |
| B | HOH942 |
| B | HOH974 |
| B | HOH976 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 4AT A 414 |
| Chain | Residue |
| A | LYS40 |
| A | THR69 |
| A | GLY71 |
| A | ASN72 |
| A | THR73 |
| A | GLN141 |
| A | GLY175 |
| A | GLY219 |
| A | PRO222 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 4AT B 914 |
| Chain | Residue |
| B | THR69 |
| B | GLY71 |
| B | ASN72 |
| B | THR73 |
| B | GLN141 |
| B | GLY175 |
| B | GLY219 |
| B | PRO222 |
| B | HOH942 |
| B | HOH963 |
Functional Information from PROSITE/UniProt
| site_id | PS00901 |
| Number of Residues | 19 |
| Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEgln.PGgSIKdRpAwyM |
| Chain | Residue | Details |
| A | LYS29-MET47 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| A | LYS40 | |
| A | SER263 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| B | LYS40 | |
| B | SER263 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| A | LYS40 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oas |
| Chain | Residue | Details |
| B | LYS40 |
