Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001817 | biological_process | regulation of cytokine production |
| A | 0005164 | molecular_function | tumor necrosis factor receptor binding |
| A | 0008063 | biological_process | Toll signaling pathway |
| A | 0032088 | biological_process | negative regulation of NF-kappaB transcription factor activity |
| A | 0033209 | biological_process | tumor necrosis factor-mediated signaling pathway |
| A | 0045087 | biological_process | innate immune response |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050688 | biological_process | regulation of defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | CYS18 |
| A | GLU19 |
| A | LYS20 |
| A | CYS21 |
| A | SER40 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
Functional Information from PROSITE/UniProt
| site_id | PS00518 |
| Number of Residues | 10 |
| Details | ZF_RING_1 Zinc finger RING-type signature. CgHrFCesCM |
| Chain | Residue | Details |
| A | CYS33-MET42 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 9 |
| Details | Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl cysteine thioester (Cys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"33608556","evidenceCode":"ECO:0000269"}]} |
2ECY
